胺碘酮联合门冬氨酸钾镁治疗阵发性室上速的疗效观察

Observation on Effect of Amiodarone Combined with Aspartate Potassium Magnesium in the Treatment of Paroxysmal Supraventricular Tachycardia

目的探讨胺碘酮联合门冬氨酸钾镁治疗阵发性室上速(PSVT)的临床效果。方法将我院PSVT患者62例随机分为观察组和对照组,对照组给予胺碘酮治疗,在此基础上观察组给予门冬氨酸钾镁联合治疗,评估两者治疗效果。结果观察组患者胺碘酮用量明显少于对照组(P<0.05);观察组患者心率转复时间明显短于对照组(P<0.05)。观察组有效率为96.77%,对照组为77.42%,两组比较差异具有统计学意义(P<0.05)。两组不良药物反应发生率比较差异无统计学意义(P>0.05)。结论胺碘酮联合门冬氨酸钾镁治疗PSVT的临床效果优于单纯应用胺碘酮,且无明显的毒副作用。

Objective To investigate the effect of amiodarone combined with aspartate potassium magnesium in treatment of paroxysmal supraventricular tachycardia. Method 62 cases with paroxysmal supraventricular tachycardia were divided into observation group and control group. The control group received the treatment of amiodarone, and the observation group received the treatment of amiodarone combined with aspartate potassium magnesium. Rexults The usage amount ofamiodarone in the observation group were fewer than those in control group （P〈0.05）. The effective rate was 96.77% in the observation group and 77.42% in the control group, and there was significant difference between the two groups （P〈0.05）. There was no significant side effect between the two groups （P〉0.05）. Conclusion The effeet of amiodarone combined with aspartate potassium magnesium in the treatment of paroxysmal supraventricular tachycardia is superior to that of the single drug ofamiodarone with few side effect.