摘要
冠状动脉介入术(PCI)是治疗冠心病的重要手段,然而PCI术后有相当部分的患者因发生心血管不良事件需再次手术或最终死亡。对其疗效、用法、使用时机、安全性等仍有不少争议。近年的研究发现,PCI术前负荷他汀治疗能有效减少心血管终点事件,改善预后。现通过对介入术前负荷他汀治疗的效果、机制、安全性等方面的文献进行综述,以期给临床研究及应用提供较系统的参考。
Percutaneous coronary intervention（PCI） is an important therapeutic regimen of coronary heart disease.However,there are a considerable proportion of patients suffering from a second operation or even death because of adverse cardiovascular events.There are still disputes over its effect,usage,time,safety and so on.In recent years,more and more clinical researches show that statin loading before PCI can effectively decrease cardiovascular endpoint events.This article summarizes the research progress in the effect,mechanism and safety of statin loading before PCI,in aiming to provide a relatively systematic reference for clinical practice.
出处
《医学综述》
2011年第5期734-737,共4页
Medical Recapitulate
关键词
冠状动脉介入术
负荷他汀
机制
效果
安全性
Percutaneous coronary intervention
Statin loading
Mechanism
Effect
Safety
