含吡啶亚甲基的S,N-烯酮缩醛的合成及生物活性

Synthesis and Bioactivity of S,N-Ketene Acetal Containing Pyridine Methylene

合成了含吡啶亚甲基的氰基、酯基或双氰基S，N-烯酮缩醛化合物．应用X射线衍射方法确定了目标化合物为E构型．生物活性测定表明，该类化合物具有很高的除草活性，并且对农作物表现出优良的选择性．

S, N-ketene acetal compounds with cyano, ester or dicyano containing pyridine methylene were synthesized, when R1 on the alkenyl bond is ester, the compound is cyanoacrylate with pyridine methylamino, which hasn' t been reported yet. The configuration of target compound 3k was determined as E by X-ray diffraction. The bioassay showed that the compounds 3k, 31 exhibited a high herbicidal activity and good selectivity with different species.