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1,5-苯并硫氮杂-α-苯基-β-内酰胺的合成、结构及谱学性质 被引量:8

Synthesis, Structure and Spectral Properties of 1, 5-Benzothiazepines-α-phenyl-β-lactams
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摘要 Four title compounds were synthesized, their spectral properties including IR,MS, 1H NMR and their steric structures were studied. The conformation of the seven-mem-bered ring is chair-like and the two phenyl substituents on the β-lactam ring adopt cis configuration. It is proposed that the reaction of 1,5-benzothiazepines with acyl chloride is a stereospecific one. Four title compounds were synthesized, their spectral properties including IR,MS, 1H NMR and their steric structures were studied. The conformation of the seven-mem-bered ring is chair-like and the two phenyl substituents on the β-lactam ring adopt cis configuration. It is proposed that the reaction of 1,5-benzothiazepines with acyl chloride is a stereospecific one.
出处 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 1999年第9期1409-1411,共3页 Chemical Journal of Chinese Universities
基金 河北省教育委员会资助
关键词 苯并硫氮杂Zhuo 苯基 内酰胺 立体专一性 合成 1,5-Benzothiazepine, Phenyl-β-lactam, Stereospecific one
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