大豆多糖的降解及其对草酸钙生长的抑制作用

Degradation of soybean polysaccharide and its inhibition on the growth of calcium oxalate

采用过氧化氢法对水提法从大豆中提取了大豆多糖(SPS)进行了降解.降解后,SPS的平均相对分子质量由115 200下降至10 200,羧基(-COOH)质量分数由13.8%下降至11.8%,特性黏度[η]由0.498 L/g下降至0.1056 L/g,溶解度由8 g/L增加至40 g/L.降解后的SPS比降解前更能抑制草酸钙晶体的生长,并增加草酸钙中二水草酸钙的比例,表明降解后的低分子质量SPS可能是一种更好的潜在绿色防石药物.

The soybean polysaccharide（SPS） extracted from soybean was degraded by using hydrogen peroxide.After degradation,the average molecular weight of SPS was decreased from 115 200 to 10 200.The percentage of carboxyl group（-COOH） and the intrinsic viscosity[η]decreased from 13.8% and 0.498 L/g to 11.8% and 0.1056 L/g,respectively,while the solubility increased from 8 g/L to 40 g/L.The degraded SPS showed much stronger capacity in inhibition of the growth of calcium oxalate crystal and in induction of calcium oxalate dehydrate,which indicates that the degraded SPS with a low molecular weight may be a better potential green anti-stone drug.