急诊PCI对急性ST段抬高型心肌梗死患者左心室功能的影响

Effects of Emergency Percutaneous Coronary Intervention on Left Ventricular Function of Patients with Acute ST-segment Elevation Myocardial Infarction

目的:探讨急诊冠状动脉介入治疗(PCI)对急性ST段抬高型心肌梗死患者左心室功能的影响。方法:入选病例为接受冠状动脉介入治疗的首次急性ST段抬高型心肌梗死的患者,65例,其中急诊PCI组35例,择期PCI组(对照组)30例。术后7 d、6个月所有患者行超声心动图检查,测量左心室射血分数、二尖瓣血流频谱以评价左心室收缩、舒张功能。术后6个月通过6 min步行试验对患者心功能作总体评价。结果:术后7 d、6个月超声心动图心功能测定结果比较差异有统计学意义,急诊PCI组左心室收缩功能、舒张功能优于择期PCI组。术后6个月6 min步行试验结果:两组比较差异有统计学意义,提示急诊PCI组心功能优于择期PCI组。结论:急诊冠状动脉介入治疗明显改善急性ST段抬高型心肌梗死患者左心室收缩及舒张功能,提高生存质量。

Objective：To investigate the effects of emergency percutaneous coronary intervention（PCI）treatment on left ventricular functions of patients with acute ST-segment elevation myocardial infarction.Methods： All cases enrolled in were 65 patients admitted for the first acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention from September 2007 to October 2009,which included 35 cases in emergency PCI group（group P） and 30 cases in selective PCI group（control group,group C）.After PCI,all patients were examined by echocardiography in 7 days and 6 months respectively.Left ventricular ejection fraction and mitral flow spectrum were measured to evaluate left ventricular systolic and diastolic functions.Overall cardiac functions were evaluated by 6-minute walking test in 6 months after PCI.Results： The left ventricular systolic and diastolic functions in group P were superior to those of group C,and the cardiac functions of group P were also significantly superior to that of group C proved by the results of 6-minute walking test.Conclusions： Emergency PCI may apparently improve left ventricular systolic and diastolic functions of patients with acute ST-segment elevation myocardial infarction,and to raise life qualities as well.