原发性肝细胞癌介入治疗的现状与进展

Recent advances in interventional therapy of hepatocellular carcinoma

临床对原发性肝细胞癌(HCC)的治疗已取得了长足进步,其中以介入放射学为主的综合治疗在整个治疗中占据重要地位.HCC的介入治疗方法主要包括以肝动脉化疗栓塞(TACE)为代表的血管内介入治疗和以局部消融为主的非血管介入治疗,而介入结合靶向治疗更进一步丰富了HCC介入治疗的内涵.本文将分别从HCC介入治疗的不同方法、原理、适应证、疗效和优缺点等方面就其治疗现状与进展作一综述.

Great progress has been made in the treatment of hepatocellular carcinoma （HCC） in recent years. Interventional therapy-containing multimodal therapy plays a predominant role in the treatment of HCC. There are mainly two intervention methods available： intervascular and non-vascular interventional therapy. Transcatheter arterial chemoembolization （TACE） and local ablation therapy are representative means of them, respectively. Interventional radiology in combination with targeted therapy further enriches the content of interventional therapy for HCC. In this article, we summarize the recent advances in interventional therapy of HCC in terms of therapeutic principles, indications, therapeutic effects, contraindications, and pros and cons of various therapeutic methods.