摘要
以MgCl2、苯磺酰苯丙氨酸(BPPA)和邻菲咯啉为原料,合成了一个新型镁配合物[Mg(BPPA)2(phen)(H2O)2].(phen).2(H2O)。对其进行了元素分析、红外光谱分析,并用X-射线衍射测定了它的单晶结构。结果表明:配合物属于三斜晶系,P空间群,配合物分子通过分子内和分子间氢键以及π-π堆积作用形成了一维链状结构。初步研究了配体及配合物的抗菌活性,配合物对大肠杆菌、白葡萄球菌及枯草芽孢杆菌有一定的抗菌活性,而配体却没有抗菌活性。
A new complex bis(N-benzenesulphonyl-L-phenylalanine-O)-bis(water-O)-(1,10-phenanthroline-N,N′)-magnesium(Ⅱ)([Mg(BPPA)2(phen)(H2O)2]·(phen)·2(H2O)),has been prepared and characterized by elemental analysis,IR spectroscopy and single-crystal X-ray diffraction.The results showed that the compound was triclinic,with P,a=07.087 0(10) nm,b=1.324 80(15) nm,c=1.621 8(2) nm,α=111.854(2)°,β=101.300(10)°,γ=95.645(10)°,V=1.361 1(3) nm3,Z=1,Mr=1 065.45,Dc=1.300 g·cm-3,T=298(2) K,F(000)=558,μ(Mo Kα)=0.176 cm-1,Flack= 0.07(11),R=0.048 4,wR=0.110 8,The complex formed one dimensional chain structure through intramolecule and intermolecule hydrogen bonds and π-π stacking.The antibacterial assay of the magnesium(Ⅱ) complex and the ligand of N-benzenesulphony-L-phenylalanine was tested using a modified version of the 2-fold serial dilution method.The complex shows considerable antibacterial activity against escherichia coli,bacillus subtilis and staphylococcus white,and the ligand did not show antibacterial activity.CCDC: 744536.
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
2011年第3期575-579,共5页
Chinese Journal of Inorganic Chemistry
基金
国家自然科学基金(No.20671073)
山东省自然科学基金(No.Y2007B60)
山东省中青年科学家奖励基金(No.2010BSA07004)
潍坊市科技发展计划资助项目
关键词
苯磺酰苯丙氨酸
Mg(Ⅱ)配合物
合成
晶体结构
抗菌活性
N-benzenesulphonyl-L-phenylalanine
magnesium complex
synthesis
crystal structure
antibactenal activity