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miRNA与血小板 被引量：2

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摘要 血栓和出血性疾病一直危害着人类的健康,血小板在其中起着关键性的作用。微小RNA(miRNA)是一类内源性非编码的小RNA,在人体生命活动中具有非常广泛的调节功能。目前发现,部分miRNA在血小板内表达,并且参与调节血小板内部相关基因的表达,为血小板内部分子机制的研究提供了一个新的途径,为血栓和出血性疾病的诊断和治疗也可能提供一种新的方法。现就miRNA与血小板相关的研究进展作一综述。
作者 梁卓 姚天明 刘丽凤 韩雅玲
机构地区 沈阳军区总医院心血管内科 第四军医大学西京医院心血管内科 辽宁中医药大学心血管内科 解放军总医院心血管内科
出处 《心脏杂志》 CAS 2011年第1期132-135,共4页 Chinese Heart Journal
关键词 MRNA 血小板
分类号 R331.1 [医药卫生—人体生理学]
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参考文献23

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同被引文献23

  • 1Faraoni I, Antonetti FR, Cardone J, et al. miR-155 gene: a typical multifunctional microRNA [ J ]. Biochim Biophys Acta, 2009, 1792 (6) :497 -505.
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  • 8Cheng Y, Liu X, Zhang S, et al. MicroRNA-21 protects against the H(2) O(2)-induced injury on cardiac myocytes via its target gene PDCD4[ J]. J Mol Cell Cardiol, 2009, 47( 1 ) : 5 - 14.
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心脏杂志
2011年 第1期

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