胆囊结石及胆囊癌病人ABO血型分布的研究

THE STUDY OF THE DISTRIBUTION OF ABO BLOOD GROUPS IN PATIENTS WITH GALLSTONE AND CARCINOMA OF GALLBLADDER

分析５２８ 例胆囊结石和６３ 例胆囊癌病人的 Ａ Ｂ Ｏ血型分布情况，并与６００ 名健康献血员的血型分布做对比研究。结果表明：胆囊结石病人 Ａ 血型占３２．０％ ， Ｂ血型占２４．５％ ， Ｏ 血型占３５．７％ ， Ａ Ｂ血型占８．５％ ，与对照组相比无显著性差异（ Ｐ＞ ０．０５），而胆囊多发性结石较多发生于 Ａ 血型病人；胆囊癌病人 Ａ 血型占４１．３％ ， Ｂ血型占２７．０％ ， Ｏ血型占２３．８％ ， Ａ Ｂ血型占７．９％ ，与对照组相比 Ａ 型血患胆囊癌的机会明显增加（ Ｐ＜ ０．０５）。提示胆囊癌与 Ａ血型有明显关联，而胆囊结石的发病机会与 Ａ Ｂ Ｏ血型无关。

In order to determine whether the distribution of ABO blood groups in patients with gallstone and carcinoma of gallbladder differs from that in general population,ABO blood groups distribution among 528 patients with gallstone and 63 patients with carcinoma of gallbladder had been studied and compared with that of 600 blood donors.The results showed that the percentage of distribution in blood group A、B、Oand AB with gallstone was 32.0%、24.5%、35.7% and 8.7% respectively,comparing with control group was not significant(P>0.05),but multiple gallstone was more common in blood group A than in others.the percentage of distribution in blood groupA、B、Oand AB with gallbladder cancer was 41.3%、27.0%、23.8% and 7.9% respectively,a statistical significance was found by compared with control group(P<0.05).the analysis indicated that gallstone is no association with any blood group and blood type A is prone to develop carcinoma of gallbladder.