回顾性研究射频消融治疗子宫肌瘤的影响因素

Retrospective study on the factors related to the treatment of uterine leiomyoma by radio-frequency caloric ablation

目的观察消融治疗子宫肌瘤的局限性、影响手术疗效的相关因素。方法 62例子宫肌瘤患者,按肌瘤大小、数目、类型、子宫位置、宫腔深度、患者年龄进行分类,用妇科多功能射频治疗仪(BBT)消融子宫肌瘤,分析其与手术时间及术中出血量的关系及手术前后肌瘤光镜、电镜下病理变化的关系。结果肌瘤大小与手术时间相关(P<0.05),各组间有统计学差异(P<0.05)。肌瘤类型与术中出血量相关(P<0.05),各组间有统计学差异(P<0.05);但与手术时间无关。而其余因素则与手术时间、术中出血量无关。结论射频消融是通过使肌瘤发生凝固性坏死来达到治疗目的的一种微创、安全、有效的方法。

Objective To provide a guide for the clinic appilications and the effectiveness prediction of radio-frequency caloric ablation therapy（BBT） by evaluating the limitations,the factors related to operative efficacy of BBT.Methods A total of 62 patients with uterine fibroids（72 uterine fibroids in total） were treated with BBT.All the operations were done by one surgeon.The patients was divided into several groups according to the different diameters,numbers,types of uterine fibroids and the lengths of uterine cavity,uterus positions,ages.We investigated the relation of operative duration,blood loss and these factors,and the pathological changes after radio-frequency caloric ablation therapy.Results Sizes of uterine fibroids were related to the operation duration（P0.05）.Types of uterine fibroids were related to the blood loss（P0.05）,but it was unconcerned with operative duration.The other factors were not related to the operation duration and the blood loss.Conclusion Radio-frequency caloric ablation therapy played a role in the treatment of uterine fibroids by coagulative necrosis,it was a less invasive,safe and effective therapeutic method.