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对数线性模型在临床试验资料分析中的应用

Application of log-linear model in clinical trial data analysis
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摘要 目的选择适合药物临床试验列联表资料分析方法,为药物的疗效、安全性和不良反应等提供科学依据。方法利用对数线性模型,讨论多维列联表分析的优势。结果与结论临床试验中经常接触到多维列联表的数据,对这类数据需采用特殊的方法进行分析处理。 Objective To choose the suitable drug clinical trials column contingency table data analysis,for the therapeutic efficacy of drugs,safety and adverse reactions and provide scientific basis.Methods Using log-linear regression model,discussing the multidimensional column contingency table analysis of the advantage.Results and conclusion Clinical trials often contact to multidimensional column contingency table data for this kind of data will be using special analyzed methods of processing.
作者 马林茂 王骏
出处 《中国临床药理学杂志》 CAS CSCD 北大核心 2011年第3期216-217,共2页 The Chinese Journal of Clinical Pharmacology
关键词 对数线性模型 主效应 交互作用 列联表 log-linear model main effect interaction effect contingency table
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