长效托宁救治有机磷农药中毒临床分析(附69例报告)

Clinical anglysis of effects of changxiaotuoning on cases of organophosphorus poisoning

目的 :通过临床对照了解长效托宁在救治有机磷农药中毒的作用和优缺点。方法 :随机将口服有机磷农药中毒患者分为对照组和试验Ⅰ组 ,经其它途径中毒者定为试验Ⅱ组。对照组应用氯磷定和常规阿托品救治 ,试验Ⅰ、Ⅱ组均应用氯磷定和长效托宁救治。结果 :对照组 16例 ,死亡 1例 ;试验Ⅰ组 35例 ,死亡 1例 ,死亡原因与长效托宁无明显关系 ;试验Ⅱ组18例 ,无死亡。在同等情况下长效托宁用药次数、用药总量均明显小于阿托品 (P <0 0 5 ) ,副作用小。结论

objective:To evaluate the advantage and the effects of Changxiaotuoning on cases of organophosphorus poisoning.Methods:51 cases of organophosphorus poisoning (opp) by digestive tract way were randomly divided into therapy group Ⅰ(n=35) and control group(n=16),18 cases of organophosphorus poisoning by other ways into group Ⅱ.The control group were treated by Pyraloximi Methochloridum and Atropine,and the therapy group Ⅰ,Ⅱ by Pyraloximi Methochloridum and Changxiaotuoning. Results:There was one case died in the control group,no case died in the therapy group Ⅱ,one case died in the therapy group Ⅰ,the cause of whose death was not with relation to Changxiaotuoning.In the same condition,Changxiaotuoning has slighter side effect and less times of treatment less total dose.Conclusion:Changxiaotuoning has an advantage over Atropine in treatment of organophosphorus poisoning.