摘要
转化生长因子β是一类多功能的细胞因子超家族,能调节细胞的增殖、分化、附着、迁移、凋亡和细胞外基质的合成等多种细胞生物学活性,存疾病的发牛发展过程中起着重要作用。本文将阐述转化生长因子β家族的成员、结构和生物学作用,及其与气管支气管结核关系的研究进展。
Transforming growth factor-β(TGF-β) is a class of multifunctional cell factor superi'amily. It can regulate cell proliferation, differentiation, adhesion, migration, apoptosis and extracellular matrix synthesis and other biological activities, and play an important role in the development of the disease. This paper reviews TGF-β family members, structure, biological function, and research progress of its relationship with tracheobronchial tuberculosis.
出处
《国际呼吸杂志》
2011年第6期462-463,共2页
International Journal of Respiration
关键词
转化生长因子Β
支气管结核
细胞因子
Transforming growth factor-β
Endobronchial tuberculosis
Cytokine