脂肪细胞线粒体功能与肥胖

Adipocyte mitochondrial function and obesity

线粒体主要存在于能量需求高、代谢强的组织，被认为是细胞的“动力工厂”，为细胞的代谢活动提供能量。肥胖的发生主要是脂质积聚过多，而脂肪细胞线粒体是脂肪酸B氧化的场所之一，脂肪细胞线粒体的脂肪酸氧化功能对于维持脂肪细胞内甘油三酯代谢有重要作用，其功能失调与肥胖的关系成为新的研究热点。

Mitochondfia are usually described as the ＂ powerhouse unit＂ of the cell, which exist in tissues with a high energy demand and a high metabolic activity, and provide energy for the metabolic activity of cell. More lipid accumulation can lead to obesity. Mitoehondria are the main sites of fatty acid ~ oxidization which are very important to adipocyte triglyceride metabolism. The relationship between mitochondrial dysfunction and obestiy has become the new research detection.