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野葛花解酒作用机理研究 被引量:15

Mechanism for the extracts from flower of Pueraria lobata to inhibit alcoholism
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摘要 目的:探讨野葛花提取物解酒作用机理,为中药解酒保肝药物的开发提供依据。方法:观察比较野葛花提取物与解酒护肝胶囊对小鼠肝脏匀浆中ADH、ALDH、SOD、GSH-PX的酶活力的影响[1]。结果:野葛花提取物能够明显提高ADH、ALDH、SOD、GSH-PX活力。结论:野葛花提取物通过提高ADH、ALDH、SOD、GSH-PX活力以达到其解酒的作用,进而对抗酒精性肝损伤。 Objective:To elucidate the mechanism for the extracts from flower of Pueraria Iobata to inhibit alcoholism in order to provide the basis on new medicine. Methods, Compared the effect of the extracts of Pueraria Iobata flower and an agent "Anti-alcoholic Liver capsule" on the activities of ADH, ALDH, SOD and GSH-Px in liver homogenate.Results:The extracts of Pueraria Iobata flower can markedly increase the activities of ADH,ALDH, SOD and GSH-Px.Conclusion-The extracts from flower of Pueraria Iobata can markedly enhance the activities of ADH,ALDH,SOD and GSH-Px to against alcohol-induced liver injury.
作者 刘莹 郁建平
机构地区 贵阳学院
出处 《食品工业科技》 CAS CSCD 北大核心 2011年第4期355-356,361,共3页 Science and Technology of Food Industry
基金 资源植物草珊瑚二次开发及种植基地建设项目基金支撑(黔科合县市(2009)7012-1)
关键词 野葛花提取物 ADH ALDH SOD GSH-PX 解酒机理 extracts from flower of Pueraria Iobata ADH ALDH SOD GSH- Px inhibit alcoholism
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