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厄多司坦对老年支气管扩张症及黏液分泌过多患者的治疗效果 被引量:14

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摘要 目的:探讨厄多司坦口服治疗对老年支气管扩张症并黏液高分泌患者的治疗效果。方法:支气管扩张症并黏液高分泌的60例老年患者随机分为两组,每组30例。研究组患者接受厄多司坦300mg每天2次口服及胸部物理治疗。对照组患者只接受胸部物理治疗。检测患者用力肺活量、动脉血气、呼吸肌力、6min步行距离、咳嗽及呼吸困难视觉模拟评分(VAS)。采用3分评分法评价气道黏液密度(MD)、脓性黏液(MP)、黏液体积(MVP)。结果:治疗10d后,两组6min步行距离、咳嗽及呼吸困难VAS评分、MD和MVP评分均有显著改善(P<0.05)。研究组患者的第1秒用力呼气量、用力肺活量和呼吸肌力明显改善(P<0.05)。研究组MVP改变较对照组明显(P<0.05)。结论:胸部物理治疗联合每天2次300mg厄多司坦口服治疗老年支气管扩张症并慢性黏液高分泌者的疗效较好。
出处 《实用医学杂志》 CAS 北大核心 2011年第6期1066-1068,共3页 The Journal of Practical Medicine
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