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帕瑞昔布钠用于妇科腹腔镜手术超前镇痛的疗效观察 被引量:3

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摘要 目的:观察帕瑞昔布钠对于妇科腹腔镜手术患者的超前镇痛作用。方法:120例择期行妇科腹腔镜手术患者随机分为A、B、C3组,每组各40例。A组在麻醉诱导时静注40kg的帕瑞昔布钠,缝皮时静注生理盐水10mL;B组在麻醉诱导时静注生理盐水10mL,缝皮时静注40kg的帕瑞昔布钠;C组在麻醉诱导和缝皮时均静注生理盐水10mL。采用视觉模拟量表(VAS)评价各时点静息时和咳嗽时的疼痛强度,并观察术后的不良反应。结果:A组和B组术后12h内静息时和咳嗽时的VAS评分均小于C组,A组和B组术后12h内镇痛效果显著。但A组和B组术后12h内静息时和咳嗽时的VAS评分的差异无统计学意义,尚未发现超前镇痛的效果。结论:帕瑞昔布可有效缓解腹腔镜手术的术后疼痛,且无明显不良反应,尚未发现超前镇痛的效果。
出处 《实用医学杂志》 CAS 北大核心 2011年第6期1077-1079,共3页 The Journal of Practical Medicine
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