天然萜类化合物在宫颈癌抗癌机制中的研究

Research Progresses on the Anticancer Mechanisms of Natural Terpenes in Cervical Cancer

随着中草药低毒高效的特点逐渐为大家认知,越来越多的中草药被用于宫颈癌的治疗。萜类化合物是中草药中一类比较重要的化合物,现已发现青蒿素、香樟醇、冬凌草甲素和大豆皂苷等多种萜类化合物表现出抗宫颈癌活性,其中二萜化合物紫杉醇已广泛应用于宫颈癌治疗,并且取得了较好的临床疗效,该类化合物的抗癌机制也正处于研究中。就萜类物质在宫颈癌抗癌机制中的研究进行综述。

More and more Chinese herbal medicine is used for the therapy of cervical cancer,as its high-efficiency and low-toxin advantages are gradually recognized.Terpenes is a class of important compounds in Chinese herbal medicine.Recently,a variety of terpenoids with anti-tumor activity have been found,such as artemisinin,Cinnamomum camphora alcohol,oridonin and soyasaponins.Among them,paclitaxel has been widely used in the treatment of cervical cancer and achieved an efficient therapeutic effects.Now,the anti-cancer mechanism of terpenes is a research topic.In this review,we comprehensively discussed the progresses of anti-cancer mechanisms of terpenoid substances in cervical cancer.