长春瑞滨联合顺铂治疗晚期乳腺癌的临床护理

Clinical Nursing Care in the Treatment of Patients with Advanced Breast Cancer by Chemotherapy with Vinorelbine and Cisplatin

目的探讨长春瑞滨联合顺铂化疗方案治疗晚期乳腺癌的护理方法与效果。方法 40例晚期乳腺癌患者入组,化疗方案:长春瑞滨40 mg/m2 d1,d8;顺铂25 mg/m2,d1～d4。结果治疗总有效率为52.5%。主要毒副反应为骨髓抑制、恶心呕吐、脱发、关节肌肉酸痛和静脉炎。主要护理方法为化疗前护理、心理护理、预防静脉炎护理、骨髓抑制护理、胃肠道反应的护理、患侧上肢水肿的护理以及脱发的护理。经上述护理措施,40例患者均顺利完成2周期化疗,无严重不良事件发生。结论长春瑞滨顺铂化疗方案治疗晚期乳腺癌的化疗过程中,护士要全面掌握化疗药物毒性反应特点,加强观察药物的毒副反应,针对化疗药物的各种不良反应,做好各项防范措施,同时做好心理护理,可以预防和减轻毒副反应,保证化疗过程的顺利和达到预期的治疗效果。

Objective To explore the nursing methods and its effect on the treatment of advanced breast cancer by chemotherapy with vinorelbine and cisplatin. Methods Forty patients were allocated to the group, they were treated with vinorelbine 40 mg/ m2 on day 1 and day 8, and cisplatin 25 mg/m2 on day 1 -4. Results The response rate was 52.5%. The main toxicity were leukopenia, gastroenteric reaction, alopeci, muscle and skeletal pain and phlebiti. The main methods of nurses care were the care before the nurses, the care of psychology, the care of prevent the phlebitis, the care of gastroenteric reaction, the care of leukope- nia, the care of alopeci and the care of edema of the arm. After the nursing care, all the 40 patients completed two terms chemo- therapy without serious toxicity. Conclusion In the chemotherapy with vinorelbine and cisplatin, nurses should grasp the charac- teristics of the reaction of drug toxicity during chemotherapy as much as possible and enhance the obsevration on drug toxicity and adverse reaction so as to take some preventive measure ;the good psychological care can prevent and reduce side-reaction and en- sure to complete the chemotherapy, and the desired therapeutic effect can be achieved.