摘要
天然抗性相关巨噬蛋白(natural resistance associated macrophage protein 1,NRAMP1)与多种胞内菌如结核分枝杆菌、沙门氏杆菌和利什曼原虫等易感和抗性相关。综述了NRAMP1基因的结构特点、作用机理、表达调控及其与疾病的相关性,以期为应用于猪的抗病育种提供理论依据。
Natural resistance associated macrophage protein 1 has been testified that it is correlation to resistance on a variety of intracellular bacteria such as Mycobacterium tuberculosis,Salmonella and Leishmania etc.In this paper,the structure characteristics of NRAMP1 gene,expression mechanism,regulation and correlation with disease was reviewed,it will provide the theoretical basis for breeding application in pig disease resistance.
出处
《畜牧与饲料科学》
2011年第1期28-30,共3页
Animal Husbandry and Feed Science
基金
山西省攻关项目(991016和20080311031)
科技部农业科技成果转化资金项目(2008GB2A300032)
关键词
NRAMP1基因
结构特点
作用机理
表达调控
NRAMP1 gene
structure characteristics
mechanism
regulation and expression
