彩超对颈动脉粥样硬化斑块与复发脑梗死关系的研究

Correlation between carotid artery atherosclerotic plaque and recurrence of cerebral infarction

目的探讨颈动脉粥样硬化(CAA)斑块与复发脑梗死的关系。方法对240例脑梗死和100例非脑梗死患者行颈动脉彩色多普勒超声检查,分析入组者的年龄、性别、伴发疾病与CAA斑块发生的关系,通过不同级别的CAA斑块在各组中的分布的情况比较,以及不同性质斑块的发生情况,来了解CAA斑块在复发脑梗死发生中的作用。结果 CAA斑块的发生与年龄、伴有高血压病、糖尿病、血脂异常明显相关(P<0.05);脑梗死组CAA斑块的发生率较非脑梗死组高(P<0.01),复发脑梗死组斑块的发生率及斑块级别更高。复发脑梗死组斑块多为扁平斑、软斑及混合斑(60%),溃疡斑少见。结论年龄、高血压病、糖尿病、血脂异常是CAA斑块形成的危险因素,CAA斑块与脑梗死的发生密切相关,复发脑梗死斑块的发生率及斑块级别更高,且多为扁平斑、软斑及混合斑(60%),溃疡斑少见。彩色多普勒超声是监测CAA斑块的最简捷的方法,对临床脑梗死的防治有重要意义。

Aim To explore the relationship of carotid artery atherosclerotic plaque and recurrence of cerebral infarction.Methods 240 patients with cerebral infarction and 100 cases without cerebral infarction were examined by carotid artery color Doppler ultrasonography.To acknowledge the role of the CAA plaques in the recurrence of cerebral infarction we analyzed the relationship between age,gender,concomitant diseases and CAA plaques,then compared the CAA plaque of different levels in the distribution of each group and the occurrence of different types of plaque.Results CAA plaques were significantly correlated with age,hypertension,diabetes,dyslipidemia（P0.05）.The incidence of CAA plaque in cerebral infarction group was higher than that of non-cerebral infarction（P0.01）.In the group of recurrence of cerebral infarction group the incidence of plaque and plaque levels were higher and mostly were flat plaque plaque,soft plaque and mixed plaques（60%）.Conclusion Age,hypertension,diabetes,dyslipidemia are risk factors for CAA plaques.CAA plaques is closely related to cerebral infarction and the incidence of recurrence of cerebral infarction plaque and plaque levels are higher.Color Doppler ultrasound is the simplest and most effective method to monitor the CAA of plaque which has clinical significance in prevention and treatment of ischemic infarction.