水溶性马来酰化壳聚糖的制备及其pH响应研究

Research on Preparation of Water-Soluble Maleoyl Chitosan and Its pH Value Response

以碳酸钠为催化剂,室温下制备了水溶性的马来酰化壳聚糖。由红外光谱分析的结果说明了马来酸酐成功接枝到壳聚糖分子上,且酰化反应后的壳聚糖的热性能较壳聚糖有了很大提高。采用MPT-2自动滴定仪和Nano-ZS粒度仪对不同pH值下的颗粒粒径和Zeta电位进行测定,发现存在2个等电点:pH=2.24和pH=5.45。

The water-soluble maleoyl chitosan（MCS） was prepared at room temperature by using sodium carbonate as catalyst.The analysis results by FT-IR show that the maleic anhydride is successfully grafted onto chitosan molecule,and the thermal properties of MCS after acylation reaction significantly increase comparing with chitosan.The particle size and Zeta potential at different pH values were determined by using MPT-2 automatic titration apparatus and Nano-ZS particle size apparatus.Two isoelectric points were found out,pH=2.24 and pH=5.45.