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溃疡性结肠炎免疫机制的研究进展 被引量：15

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摘要 溃疡性结肠炎（Ulcerative colitis。UC）与克罗恩病（Crohn’s disease，CD）同属炎症性肠疾病（Inflammatory bowel disease．IBD），是一种主要累及直肠、结肠黏膜的慢性非特异性炎症，以腹痛、腹泻、黏液血便、里急后重为主要临床表现。该病迁延不愈，长达几十年。亦有发生癌变的可能性。
作者 路晓红 杨恩来 赵霞 程艳婷 王艳珍 冀来喜
机构地区 山西省中医药研究院 山西省针灸研究所 天津中医药研究院 山西中医学院
出处 《山西中医学院学报》 2011年第1期66-69,共4页 Journal of Shanxi College of Traditional Chinese Medicine
基金 国家自然科学基金(C190301)
关键词 溃疡性结肠炎 免疫机制 发病机制
分类号 R656 [医药卫生—外科学]
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参考文献29

  • 1Zhang H,Ozaki I,Mizuta T,et al. Involvement of programmed cell death 4 in transforming growth factor-betal-induced apoptosis in human hepatoeellular carcinoma [J]. Oncogene,2006,25 (45) :6 101-6 112.
  • 2马刚,郭克建,张浩,尾崎岩太,松桥幸子,郑新宇,董明.程序性细胞死亡因子4在胰腺癌组织中的表达及临床病理学意义[J].中国医学科学院学报,2005,27(5):597-600. 被引量：11
  • 3Cmarik J L,Min H,Hegamyer G,et al. Differentially expressed protein Pded4 inhibits tumor promoter-induced neoplastic transformation[J]. Proc Natl Acad Sci USA, 1999,96(24) : 14 037-14 042.
  • 4Yang H S,Jansen A P,Komar A A,et al. The transformation suppressor Pdcd4 is a novel eukaryotie translation initiation factor 4A binding protein that inhibits translation[J]. Mol Cell Biol,2003,23 ( 1 ) : 26-37.
  • 5Laronde-Leblanc N,Santhanam A N, Baker A R,et al. Struetural basis for inhibition of translation by the tumor suppressor pdcd4[J]. Mol Cell Biol, 2007,27( 1 ) : 147-156.
  • 6Dorrello N V,Peschiaroli A,Guardavaccaro D,et al. S6K1 and β TRCP-mediated degradation of PDCD4 promotes protein transla- tion and cell growth[J]. Science,2006,314(5 798):467-471.
  • 7Zakowicz H,Yang H S,Stark C,et al. Mutational analysis of the DEAD-box RNA helicase elF4All characterizes its interaction transformation suppressor Pdcd4 and elF4GI [J]. RNA,2005,11 (3) :261-274.
  • 8Yang H S,Matthews C P,Clair T,et al. Tumorigenesis suppressor Pded4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion [J]. Mol Cell Biol,2006,26(4) : 1 297-1 306.
  • 9Yang H S, Knies J L,Stark C,et al. Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation[J]. Oncogene, 2003,22(24) :3 712-3 720.
  • 10Lankat-Buttgereit B,Gregel C,Knolle A,et al. Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type 11 [J]. Mol Cell Endocrinol,2004,214(1-2) : 149-153.

二级参考文献8

  • 1Chen Y, Knosel T, Kristiansen G, et al. Loss of PDCD4expression in human lung cancer correlates with tumor progression and prognosis. J Pathol, 2003, 200(5):640-646.
  • 2Yoshinaga H, Matsuhashi S, Fujiyama C, et al. Novel human PDCD4 (H731) gene expressed in proliferative cells is ex- pressed in the small duct epithelial cells of the breast as revealed by an anti-H731 antibody. Pathol Int, 1999, 49(12):1067-1077.
  • 3Soejima H, Miyoshi O, Yoshinaga H, et al. Assignment of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization. Cytogenet Cell Genet, 1999, 87(1-2):113-114.
  • 4Matsuhashi S, Yoshinaga H, Yatsuki H, et al. Isolation of a novel gene from a human cell line with Pr-28 mAb which recognizes a nuclear antigen involved in the cell cycle. Res Commun Biochem Cell Mol Biol, 1997, 1(1):109-120.
  • 5Yoshinaga H, Matsuhashi S, Ahanek J, et al. Expression and identification of H731 gene product in HeLa cells.Res Commun Biochem Cell Mol Biol, 1997, 1(1):121-131.
  • 6Lankat-Buttgereit B, Goke R. Programmed cell death protein 4 (PDCD4): a novel target for antineoplastic therapy? Biol Cell, 2003, 95(8):515-519.
  • 7Yang HS, Knies JL, Stark C, et al. Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting Ap-1 transactivation. Oncogene, 2003, 22(24):3712-3720.
  • 8Goke A, Goke R, Knolle A, et al. DUG is a novel homologue of translation initiation factor 4G that binds eIF4A.Biochem Biophys Res Commun, 2002, 297(1):78-82.

共引文献10

同被引文献132

引证文献15

二级引证文献112

山西中医学院学报
2011年 第1期

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