1807例脂肪性肝病与相关危险因素关系的分析

The prevalence of fatty liver among government employees in Lishui city,Zhejiang

目的分析脂肪性肝病特别是非酒精性脂肪性肝病的患病率与相关危险因素的关系。方法对所辖地区部分公职人员的人体学指标和血脂、血糖及腹部B型超声波等进行检查,参数采用χ2检验和相关分析,P〈0.05为差异有统计学意义。结果资料完整应检者8 580人中脂肪性肝病1 807例,患病率21.06%。其中体质指数（BMI）不足者3例（0.17%）,正常者314例（17.38%）、超重者1 098例（60.76%）及肥胖者392例（21.69%）;各年龄组别患病例数分别为：20~岁79例（4.37%）、30~岁375例（20.75%）、40~岁625例（34.59%）、50~岁415例（22.97%）、〉60岁313例（17.32%）;本组病例中高甘油三酯症844例（46.71%）、高胆固醇症97例（5.37%）、混合性高脂血症432例（23.91%）、高血压318例（17.60%）、空腹血糖受损247例（13.67%）和糖尿病150例（8.30%）。脂肪性肝病6种危险因素χ2检验差异均有性统计学意义,与高血压、甘油三酯、总胆固醇和血糖4种危险因素均有正相关性。结论该地区公职人员脂肪性肝病患病率高,疾病的发生和发展可能与多种危险因素存在有密切联系。

Objective To investigate the prevalence of non-alcoholic fatty liver among the government employees in Lishui city,Zhejiang province.Methods The government employees of Lishui city had physical examination,ultrasonic exam and laboratory testing for blood glucose,cholesterol and triglyceride,etc.The prevalence of fatty liver and other associated conditions were analyzed.Results The prevalence rate of fatty liver was 21.1%（1 807/8 580） among government employees.Overweight,adiposity and abnormal BMI were reported in 60.8%,21.7% and 17.38% of fatty liver employees.4.4% of fatty liver patients were aged 20-29 years,20.8% aged 30-39 years,34.6% aged 40-49 years,23% aged 50-59 years and 17.3% aged over 60 years.The fatty liver completing symptoms included hypertriglyceridemic（46.7%）,hypercholesterolemia（5.4%）,higher blood pressure（17.6%）,higher blood-fasting sugar（13.7%） and diabetes（8.3%）.Fatty liver was positively correlated with hypertension,triglyceride,cholesterol and hyperglycosemia.Conclusion The government employees of Lishui city had a high risk of fatty liver and related physical conditions.