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鸦片类毒品毛细管区带电泳及场放大在线富集条件的优化 被引量：1

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摘要 通过对毛细管区带电泳(CZE)条件及场放大样品堆积(FASS)富集条件进行优化,建立简单、灵敏、可靠的鸦片类毒品的FASS-CZE检测方法。采用pH 3的100mmol/L磷酸盐缓冲液(其中含20%甲醇和5%的异丙醇)为分离缓冲液,1.3736kPa下引入水柱2 s后电迁移进样20s,在毛细管中浓缩样品组分,对吗啡、6-单乙酰吗啡和可待因3种毒品进行分离测定,可检测到的上述毒品质量浓度为2 ng/mL,与常规CZE比较,检测的灵敏度可提高约1 000倍。该方法可用于生物检材中海洛因及其代谢物的检测。
作者 王燕燕 孟品佳 王彦吉
机构地区 中国人民公安大学刑事科学技术系
出处 《中国人民公安大学学报（自然科学版）》 2010年第4期15-20,共6页 Journal of People’s Public Security University of China(Science and Technology)
基金 北京教育委员会共建项目建设计划 项目编号:SYS1004100436
关键词 毛细管区带电泳 场放大样品堆积 海洛因代谢物
分类号 D919.1 [医药卫生—法医学]
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参考文献14

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同被引文献14

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中国人民公安大学学报（自然科学版）
2010年 第4期

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