一氧化氮及降钙素基因相关肽在肺炎并发心力衰竭的变化

The changes of nitric oxide and calcitonin gene related-peptide in patients with pneumonia complicated with heart failure

目的 :探讨肺炎和肺炎并发心力衰竭 (肺炎心衰 )病人血浆一氧化氮和降钙素基因相关肽 ( CGRP)水平变化。方法 :采用生化分析法测定一氧化氮 ,放射免疫分析法测定各患者 CGRP。结果 :肺炎及肺炎心衰病人一氧化氮及降钙素基因相关肽有明显改变。结论 :提示一氧化氮及 CGRP与肺循环、缺氧有关。

Objective: To study the changes of plasma nitric oxide (NO) and calcitonin gene related peptide (CGRP) in patients with pneumonia and complicated with heart failure Methods:Plasma levels of NO and CGRP were detected by biochemical assay and radioimmunoassay respectively Results:Significant changes of NO and CGRP were found in patients with pneumonia and complicated with heart failure Conclusion:The changes of NO and CGRP are closely related to pulmonary circulation and hypoxia