前列腺增生症发病情况的调查

An epidemiological study of BPH in Chinese

目的 了解常州及武进地区前列腺增生症（ＢＰＨ） 的发病情况。 方法 调查该地区４０ 岁以上男性２ ４３３ 人的国际前列腺症状评分（ＩＰＳＳ） 、生活质量评分（Ｌ） 、最大尿流率（Ｑｍａｘ） 、前列腺体积（Ｖ） 及剩余尿（Ｒ）等情况，其中城镇职工１ ０８９ 人，农民１ ３４４ 人，测量１１８ 人血睾酮（Ｔ） 、双氢睾酮（ＤＨＴ） ，询问１ ９５７ 人性活动情况。 结果 ＢＰＨ 发病率占总调查人数（２ ４３３） 的２５．７ ％ ，城镇职工３０．４ ％ ，农民２１．９ ％ ；ＢＰＨ 组血ＤＨＴ 明显高于正常组（ Ｐ＜ ０ ．０１） ；初次性交时间早及失去性功能年龄大者ＢＰＨ 发病率高（ Ｐ＜ ０ ．０１） 。 结论 城镇职工ＢＰＨ 的发病率高于农民，血ＤＨＴ 升高与ＢＰＨ 的发生有关，初次性交时间早（ ＜ ２５ 岁） 及性功能维持年限长与ＢＰＨ

Objective To investigate the incidence of benign prostatic hyperplasia (BPH) in Changzhou and Wujin districts. Methods An investigation of the incidence of BPH in 2 433 male inhabitants over 40 years of age,1 089 urban and 1 344 rural,has been carried out including I PSS,life quality (L),Qmax,volume of prostate (V) and residual urine(R) studies.Plasma testosterone and dihydrotestosterone were assayed in all the subjects investigated.Sexual behavior was recorded in 1957. Results The incidence of BPH was 25.7%,being 30.4% in the urban habitants and 21.9% in the rural.A significant increase of dihydrotestosterone was noted in BPH subjects.The earlier the age of the occurrence of first sexual intercourse and the later the loose of sexual activity in the aged the higher would be the incidence of BPH ( P <0.01). Conclusions The increase of BPH has been higher in the urban inhabitants.The increase of plasma dihydrotestosterone might play a role in the development of BPH.The earlier the age of the occurrecnce of first sexual intercourse and the later the loose of sexual activity in the elders were associated with a higher incidence of BPH.