肺气肿合并肺间质纤维化的临床研究

The clinical study of pulmonary emphysema with pulmonary fibrosis

目的 总结肺气肿合并肺间质纤维化的临床特点并探讨其临床意义。方法 分析５ 年来我院确诊的１１ 例肺气肿合并肺间质纤维化患者的症状、Ｘ线胸片、血气分析、肺功能、ＣＴ结果。结果 肺气肿合并肺间质纤维化患者多具有较长的吸烟史，临床表现介于上述两种病变之间，其肺功能测定结果不完全符合阻塞型或限制型通气功能障碍，Ｘ 线及ＣＴ兼具二者的特点。结论 尽管肺气肿和肺间质纤维化是两种不同的疾病，但是确实可以并存，且具有其独特的临床表现，胸部高分辨ＣＴ（ＨＲＣＴ）往往能为临床提供重要的诊断依据。

Objective Emphysema and interstitial pulmonary fibrosis are two different diseases in clinical manifestation and pathology, but it was noticed that there were cases diagnosed as pulmonary emphysema and pulmonary fibrosis It is necessary to study the relationship between the clinical aspects of these cases Methods 11 patients with emphysema and pulmonary fibrosis were found in the past five years Clinical symptoms, radiographic features, arterial blood gas, lung funtion testing and computed tomography of the chest were analyzed Results These patients had a long history of cigarette smoking , Their clinical features are those of both emphysema and pulmonary fibrosis Conclusions Although emphysema and interstitial pulmonary fibrosis are two different diseases, they could coexist in some patients Their clinical features do not like either of the two diseases HRCT is an important method for discovering the coexistance of pulmonary emphysema and interstitial fibrosis