吸烟、饮酒因素与糖尿病关系的病例对照研究

A Case Control Study on Relationship Between Smoking or Drinking and Diabetes

在江苏省糖尿病流行特征研究的基础上,对新诊断出来的糖尿病( DM) 和糖耐量低减(IGT) 患者分别与同性别、同年龄组( 相差不超过5 岁) 、同职业、同文化程度、同一地区居住5 年以上的非糖尿病非IGT 的“健康”对照进行1∶1 配比,分别配成215 对和467 对。对吸烟和饮酒情况进行分析,发现吸烟与DM 有关,大量吸烟者( 曾经吸烟≥26 支/ 日) 发生DM 的OR 为5-60 ,随着每日吸烟支数的增加,发生DM 的OR 有增高的趋势;但吸烟与IGT 无相关关系。配比分析提示饮酒与DM 、IGT 均无关,但大量饮酒者( 曾经酒精消耗量≥35kg/ 年)发生IGT 的OR 为2-40 。

On the basis of epidemiological survey on diabetes mellitus (DM) in jiangsu province, we conducted a case control study to investigate the relationship between smoking or drinking and diabetes. Newly diagnosed diabetes and impaired glucose tolerance (TGT) patients were matched by their own controls respectively. Our result showed smoking was related to DM. Those who smoked more than 26 cigarettes per dav were in higher risk of DM, the odds ratio of ever smokers was 5 60. The more cigarettes an individual smoked in a day, the higher risk he would take in DM. We hadn' t found smokingwas in relation with IGT. Drinking habits, unlike smoking, was proved not to be the risk factor of DM or IGT according to our study, but if consuming up to 35 kilograms pure alcohol per year, one would have a higher risk in IGT.