苯妥英促进骨折愈合的临床观察

CLINICAL OBSERVATION OF PHENYTOIN IN PROMOTING FRACTURE HEALING

目的 观察苯妥英对骨折愈合的促进作用。方法 选择40 例胫腓骨闭合性骨折患者,随机分为两组,治疗组用苯妥英和接骨丹口服,对照组仅用接骨丹口服。术后分期观察一般情况,纵向叩击痛,骨折临床愈合时间,X线片骨痂生长情况。结果 全部患者骨折均在伤后3个月内愈合,但治疗组纵向叩击痛、临床愈合时间及X线片骨痂生长均明显优于对照组。结论 口服苯妥英有明显的促进骨折愈合的作用。由于中成药接骨丹含有钙成分。

Objective To observe the promoting effect of phenytoin on fracture healing.Methods Fourty cases with close fractures of tibia and fibula were included and divided into two groups randomly:the experimental group was administrated with phenytoin and Chinese traditional drug Jiegudan orally,while the control group was given Jiegudan only.Longitudinal percussion pain,clinical healing time of fracture, growth of calus in X ray film were detected to evaluate the clinical result.Results All the fractures were healed in 3 months.But the experimental group was superior to the control group in all indexes.Condusion Administration of phenytoin orally can markedly promote fracture healing.