转化细胞与致瘤性综述

REVIEW ON TRANSFORMED CELL AND TUMORIGENICITY

目的 探讨转化细胞特性及与致瘤性的关系。方法 广泛查阅近期有关转化细胞和致瘤性方面的文献,综述其内容。结果 一般转化细胞无致瘤性,大都能保持其正常细胞的生物学特性和功能,而恶性转化细胞其生物学特性和功能明显改变。

Objective To explore the relationship between characteristics of transformed cell and tumorigenicity.Methods Documents about transformed cell and tumorigenicity were reviewed in detail.Results Normal biological characteristics and cell function could be maintained in non tumorigenic transformed cell, but it was changed markedly in malignant transformed cell.Conclusion Non tumorigenic transformed cell can be served as a standard cell line to study the function and growth characteristics of normal cell.