诊断剂量超声波对早孕胚胎的生物学效应

Biological Effects of Diagnostic Ultrasound on Human Embryos in Uterus

对经腹超声及经阴道超声辐照后的宫内胎囊进行生化和遗传学研究，探讨诊断剂量超声波对胚胎是否安全。方法：将拟行人工流产的６０例早孕妇女随机分成３组：Ⅰ组为对照组，Ⅱ组为经腹超声１０分组，Ⅲ组为经阴道超声１０分组。Ⅱ、Ⅲ组分别于超声辐照后１小时行人工流产术。结果：Ⅲ组丙二醛（ＭＤＡ）升高，超氧化物歧化酶（ＳＯＤ）降低，与Ⅰ组相比有显著性差异。Ⅱ、Ⅲ组姊妹染色单体互换（ＳＣＥ）频率与Ⅰ组相比无显著性差异。结论：对早孕妇女应避免阴道超声检查，采用经腹超声且不宜超过１０分。

This paper gives a study of biochemical and genetic changes in villous cells in early pregnancy women after ultrasonic dosage was exposed in uteri to assess whether it is harmful to the embryos. Methods:60 cases of early pregnant women were divided into three groups(I, control group, group Ⅱ and Ⅲ) 1 hour after respctively expeured to abdomi- nosongraph and vaginosonograph for 10 minutes, followed by induced abortion. Results: The value of MDA was increased while the level of SOD was decreased in group Ⅲ. The differences between group Ⅰ and group Ⅲ were statistically obvious. The sister chromatid exchange(SCE)of group Ⅱ and Ⅲ had no significant differences. Conclusion: Vaginosonograph should be avoided and abdominosonograph shorld be used for no longer than 10 minutes in early pregnancy women for clinical diag- nosis.