扩张型心肌病与细胞因子基因多态性研究进展
被引量:1
摘要
扩张型心肌病(Dilated cardiomyopathy,DCM)是一种以单侧或双侧心腔扩大,心肌收缩功能减退,伴或不伴有充血性心力衰竭为主要特征的心肌疾病。临床表现主要为进行性心力衰竭、心律失常、血栓栓塞,甚或猝死,到目前来说尚缺乏特异性治疗,预后极差。
出处
《赣南医学院学报》
2010年第6期998-999,共2页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
参考文献22
-
1Grimm W,Rudolph S,Christ M,et al.Prognostic significance of morphometric endomyocardial biopsy analysis in patients with idiopathic dilated cardiomyopathy[J].Am Heart J,2003,146(2):372-376.
-
2李秀玉,辛晓敏,刘凤岐.白细胞介素在扩张型心肌病患者血清中的表达及意义[J].中国实验诊断学,2009,13(8):1035-1037. 被引量:3
-
3王慧敏,张桂红,牛辉.扩张型心肌病患者血清白细胞介素-8改变的意义[J].前卫医药杂志,2000,17(1):37-37. 被引量:1
-
4黄萍,周斌,张林,刘星,陈斌,饶莉.IL-2基因多态性与中国汉族人群特发性扩张型心肌病的相关性研究[J].中华医学遗传学杂志,2008,25(3):322-325. 被引量:4
-
5Pankuweit S,Portig 1,Maisch B.Pathophysiology of cardiac inflammation:molecular mechanisms[J].Her/,2002,27(7):669-676.
-
6Gaffen SL,Liu KD.Overview of interleukin-2 function,production and clinical applications[J].Cytokine,2004,28(3):109-123.
-
7Matesanz F,Fedetz M,Collado-Romero M,et al.Allelic expression and interleukin-2 polymorphisms in multiple sclerosis[J].J Neuroimmunol,2001,119(l);101-105.
-
8Morgun A,Shulzhenko N,Rampim GF,et al.Interleukin-2 gene polymorphism is associated with renal but not cardiac transplant outcome[J].Transplant Proc,2003,35(4):1344-1345.
-
9Schwarz MJ,Kronig H,Piedel M,et al.IL-2 and IL-4 polymorphism as candidate genes in schizophrenia[J].Eur Arch Psychiatry Clin Neurosci,2006,256(2):72-76.
-
10Isaacs A,Lindenmann J,Virus interference.I.The interferon[J].Proc R Sue Lond B Biol Sci,1957,147(927):258-267.
二级参考文献35
-
1刘巍,李为民,刘颖,尹鹏志,王政,张瑞红,孙宁玲.中国北方汉族人群人类白细胞抗原-DQA1及-DQB1基因第二外显子多态性与扩张型心肌病遗传易感性研究[J].中国循环杂志,2005,20(1):41-44. 被引量:6
-
2董波,潘景韬,潘祥林,王飒,宋素芹,邵建华.扩张型心肌病白细胞介素2受体的初步研究[J].中华心血管病杂志,1994,22(1):60-61. 被引量:10
-
3WEI LIU,WEI MIN LI,CHENG GAO,ZHENG WANG,RUI HONG ZHANG,YI HUI KONG.Cytotoxic T lymphocyte associated antigen-4 gene exon 1A49→G polymorphisms confer susceptibility to idiopathic dilated cardiomyopathy[J].Journal of Microbiology and Immunology,2005,3(2):131-135. 被引量:1
-
4曹峰林,孙政育,方胜,王春梅.特发性扩张型心肌病与HLA-A*基因的关联研究[J].中国地方病学杂志,2005,24(6):607-608. 被引量:2
-
5刘巍,李为民,高成,李悦,孔一慧.CTLA-4基因启动子区单核苷酸多态性与特发性扩张型心肌病的关联研究[J].中华医学遗传学杂志,2006,23(2):198-201. 被引量:5
-
6Grunig E, Tasman JA, Kucherer H, et al. Frequency and phenotypes of familial dilated cardiomyopathy[J].J Am Coll Cardiol, 1998,31 ( 1 ) : 186-194.
-
7Messer G, Spengler U, Jung MC. Polymorphic structure of the tumor necrosis factor(TNF) locus: an Neo Ⅰ polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production[J].J Exp Med, 1991,173( 1 ) :209-214.
-
8Bowles NE, Bowles KR, Towbin JA. The "final common pathway" hypothesis and inherited cardiovascular disease. The role of cytoskeletal proleins in dilated canliomyopathy[J].Herz.2000, 25(3 ) : 168-175.
-
9Brdham WS,Moe G,Wndt KA,et al.TNF-alpha and myocardial matrix metalloproteinases in heart failure:relationship to LV remodeling[J].Am J Physiol Heart Circ Physiol, 2002,282 (4) : H 1288-H 1295.
-
10Pankuweit S, Portig I, Maisch B. Pathophysiology of cardiac inflammation: molecular mechanisms[J].Herz,2002,27(7):669- 676.
共引文献10
-
1陆莹,杨爽,马珊珊,李呼伦,于波.组蛋白脱乙酰基酶2在血管紧张素Ⅱ致心肌细胞肥大中的表达[J].中国地方病学杂志,2005,24(4):392-395. 被引量:1
-
2李佳,富路,葛海龙,陈光远,孙俊峰.心房快速起搏致扩张型心肌病犬模型心肌基质细胞衍生因子-1及其受体的表达[J].中国地方病学杂志,2006,25(5):514-516. 被引量:3
-
3廖永玲,廖伟.扩张性心肌病与细胞因子基因多态性相关性的研究进展[J].赣南医学院学报,2013,33(1):154-155.
-
4杨浩,彭瑛,李娅姣,付锴,谢秋,周斌,饶莉.程序性细胞死亡因子1基因单核苷酸多态性与中国扩张型心肌病的相关性研究[J].中华医学遗传学杂志,2014,31(3):362-366. 被引量:3
-
5方柳惠,范晓晨.小儿病毒性心肌炎与基因多态性的相关性研究进展[J].国际儿科学杂志,2015,42(3):320-323. 被引量:2
-
6李志芳,段成城,董丽妍.扩张型心肌病外周血炎性因子水平及其临床意义[J].检验医学与临床,2016,13(1):88-90. 被引量:6
-
7代小惠,彭瑛,周斌,李春梅,宋慧子,窦青瑜,谢晓川,饶莉.抑瘤素M受体基因多态性与中国汉族人群扩张型心肌病的相关性[J].中华医学遗传学杂志,2018,35(2):210-214. 被引量:2
-
8周莉,陈海燕,孔山,成家茂.干扰素-γ基因多态性与扩张型心肌病相关性研究[J].大理大学学报,2017,2(8):28-30.
-
9杜培儒,王颖婷,谭武红.TGFβ2基因单核苷酸多态性与陕西省克山病的关联研究[J].中华地方病学杂志,2022,41(11):861-865.
-
10姚凤华,张利,陈香美.白细胞介素35与疾病[J].中华临床医师杂志(电子版),2017,11(3):497-501. 被引量:2
同被引文献29
-
1Corsten MF, Schroen B, Heymans S. Inflammation in viral myocardi- tis : friend or foe? [ J]. Trends Mol Med ,2012,18 ( 7 ) :426-437.
-
2Jeserich M,Brunner E,Kandolf R ,et al. Diagnosis of viral myocardi- tis by cardiac magnetic resonance and viral genome detection in pe- ripheral blood[J]. Int J Cardiovasc Imaging,2013,29( 1 ) :121-129.
-
3Bowles NE, Javier Fuentes-Garcia F, Makar KA, et al. Analysis of the coxsackievirus B-adenovirus receptor gene in patients with myocardi- tis or dilated cardiomyopathy [ J ]. Mol Genet Metab, 2002,77 ( 3 ) : 257-259.
-
4Kashimura T, Kodama M, Hotta Y, eta/. Spatiotemporal changes of coxsackievirus and adenovims receptor in rat hearts during postnatal development and in cultured cardiomyocytes of neonatal rat[ J]. Vir- chows Arch,2004,444(3) :283-292.
-
5Staab J, Ruppert V, Pankuweit S, et al. Polymorphisms in genes enco- ding nonsarcomeric proteins and their role in the pathogenesis of di- lated cardiomyopathy [ J ]. Herz, 2012,37 ( 8 ) : 836 -841.
-
6Pankuweit S, Ruppert V, J6nsd6ttir U, et al. The HLA class II allele DQB1 * 0309 is associated with dilated cardiomyopathy [ JJ. Gene, 2013,531 (2) :180-183.
-
7Dhillon SS ,Mastropaolo LA,Murchie R,et al. Higher activity of the inducible nitric oxide synthase contributes to very early onset infam- matory bowel disease [ J ]. Clin Transl Gastroenterol, 2014,5 ( 1 ) : e46.
-
8Matsa LS, Rangaraju A, Vengaldas V, et al. Haplotypes of NOS3 gene polymorphisms in dilated cardiomyopathy [ J ]. PloS One,2013, 8(7) :e70523.
-
9Ikeda K,Ihara K,Yamaguchi K,et al. Genetic analysis of MMP gene polymorphisms in patients with Kawasaki disease[J]. Pediatr Res, 2008,63 (2) :182-185.
-
10Westermann D, Savvatis K, Schultheiss HP, et al and matrix metalloproteinases in viral myocarditis [ J ]. J Mol Cell Cardio1,2010,48 (3) :468-473.
-
1申屠敏华.扩张型心肌病临床表现51例分析[J].临床医学,2011,31(2):104-104. 被引量:2
-
2吕淼.幽门螺杆菌感染与糖尿病伴消化道症状患者基因多态性相关性[J].中外医疗,2009,28(18):35-36.
-
3乙肝患者的细胞因子基因多态性[J].传染病网络动态,2003(2):24-24.
-
4HLA和细胞因子基因多态性与HBV接种反应呈独立相关性[J].传染病网络动态,2004(8):27-27.
-
5零达红,凌佩莹.126例扩张型心肌病患者心律失常分析[J].内科,2007,2(5):749-750.
-
6高晓飞,许轶洲.扩张型心肌病治疗手段的进展[J].心脏杂志,2016,28(4):488-491. 被引量:13
-
7宋友恩,李涛仪,马春梅.苯那普利和倍他乐克治疗扩张型心肌病36例[J].武警医学,2005,16(8):616-617.
-
8林丽花,王慧华.扩张型心肌病患者的护理[J].实用心脑肺血管病杂志,2012,20(12):2055-2056.
-
9王国政,朱安平,李红旗,王会平,汪晖,宋志杰.扩张型心肌病并发室性心动过速电复律成功一例[J].海南医学,2011,22(20):130-131. 被引量:2
-
10李寿勋,赵小慧.扩张型心肌病18例误诊分析[J].中国煤炭工业医学杂志,2011,14(8):1214-1215.