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中老年人血尿酸与颈动脉内膜中层厚度的临床分析

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摘要 目的探讨中老年人颈总动脉平均内膜中层厚度(IMT)和血尿酸水平的相关性。方法应用彩色多普勒超声检测104例中老年人颈总动脉平均IMT、同时行血尿酸检查,按血尿酸水平分为尿酸正常组、高尿酸血症组,分析血尿酸与颈动脉内膜中层厚度的相关性。结果高血压、颈动脉内膜厚度、胆固醇、HDL-C及Apo-a均有统计学意义(P<0.05),即高尿酸血症组高血压、颈动脉内膜厚度及胆固醇明显高于尿酸正常组(P<0.05),但HDL-C及Apo-a明显低于尿酸正常组(P<0.05)。结论高尿酸血症组高血压患者明显增加,颈总动脉内膜中层厚度增加,胆固醇水平有意义地增高,相反高密度脂蛋白和载脂蛋白a明显降低,血尿酸可能是动脉粥样硬化的早期标记。
出处 《中国医药指南》 2011年第8期84-85,共2页 Guide of China Medicine
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  • 1Suttorr TyrrellK,AlcomHG,WolfsonSK,Kelsey SF,KullerLH.Predictors of carotid stenosis in older adults with and without isolated systolic hypertension[ J ].Strike,1993,24:355-361.
  • 2Rosa EM,Kramer C,Castro I..Association between coronary artery atherosclerosis and the intima- media thickness of the common carotid artery measured on ultrasonography [J].Arq Bras Cardiol,2003,80(6) :589-92.
  • 3BonithorrkoppC,Touboul PJ,BerrC,etal.Relation of intima-media thickness to atherosclerotic plaque in carotid ateries [ J ].Arterioscler thromb vasc Biol,1996,16:310-316.
  • 4Hansa G,Bhargava K,Bansal M,etal.Carotid intima- media thickness and coronary artery disease:an Indian perspective[J ].Asian Cardiovasc Thorac Ann,2003,11(3) :217-21.
  • 5Schlesinger N.Dietary factors and hyperuricaemia. Curr PharmDes . 2005
  • 6Brand FN,McGee DL,Kannel WB,et al.Hyperuricemia as arisk factor of coronary heart disease:the framingham study. American Journal of Epidemiology . 1985
  • 7Sakai H,Shichiri M,Hirata Y.Hypouricemia in diabetes melli-tus. Japanese Journal of Clinical Medicine . 2003
  • 8Ariel RJ.Significance of uric acid for the heart and vessels. European Heart Journal . 2006
  • 9Ishihara M,Shinoda T,Aizawa T,et al.Hypouricemia in NID-DM patients. Diabetes Care . 1988
  • 10Arai K,Yamasaki Y,Kajimoto Y,et al.Association ofmethylenetetrahydrofolate reductase gene polymorphism withcarotid arterial wall thickening and myocardial infarction risk inNIDDM. Diabetes J . 1997

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