无创呼吸机联合纳洛酮治疗慢性阻塞性肺疾病并发Ⅱ型呼吸衰竭的效果分析

The Curative Effect of Noninvasive Ventilator plus Naloxon on Chronic Obstructive Pulmonary Disease Combined with Respiratory Failure Type Ⅱ

目的探讨无创呼吸机联合纳洛酮治疗慢性阻塞性肺疾病并发Ⅱ型呼吸衰竭的临床效果。方法将我院2009年10月～2010年7月收治的慢性阻塞性肺疾病并发Ⅱ型呼吸衰竭患者85例,随机分为观察组(n=43)和对照组(n=42)。对照组患者采用常规方法治疗,观察组加用无创呼吸机联合纳洛酮治疗,比较两组患者的临床效果。结果观察组的总有效率为97.7%,对照组为81.0%,两组有显著性差异(P<0.05);治疗后观察组PaO2、SpO2显著高于对照组(P<0.05),PaCO2显著低于对照组(P<0.05)。结论无创呼吸机联合纳洛酮治疗慢性阻塞性肺疾病并发Ⅱ型呼吸衰竭的效果满意,值得推广。

Objective To discuss the clinical curative effect of noninvasive ventilator plus naloxon on chronic obstructive pulmonary disease combined with respiratory failure type II. Methods 85 cases with chronic obstructive pulmonary disease combined with respiratory failure type II hospitalized in my hospital from Oct.,2009 to July,2010 were randomly divided into 2 groups： observation group（n=43） and control group（n=42）;routine treatment was given to patients in both groups while noninvasive ventilator plus naloxon was added to patients in observation group;a comparison was made between the curative effects of the 2 groups. Result The rate of the total effect in observation group was 97.7% while that in control group was 81.0%;there existed a significant difference between the 2 groups（P0.05）;the PaO2 and SpO2 of observation group after treatment was obviously higher than those of control group（P0.05） and PaCO2 of observation group was obviously lower than that of control group（P0.05）. Conclusions Noninvasive ventilator plus naloxon is of satisfactory curative effect in treating chronic obstructive pulmonary disease combined with respiratory failure type II.