轮状病毒肠炎致心、肝、肾损害的临床分析

Clinical analysis of rotavirus enteritis induced by myocardial,hepatic and renal damage

目的探讨婴幼儿轮状病毒(RV)肠炎与心、肝、肾损害的关系。方法对126例腹泻患儿行大便RV抗原检测,按照大便RV抗原检测结果分为观察组(大便RV抗原阳性组)68例及对照组(大便RV抗原阴性组)58例,对2组心、肝、肾主要生化标志物检测结果进行对比分析。结果观察组心、肝、肾损害发生率高于对照组,差异有统计学意义(P<0.01);观察组失水程度与心肌、肝、肾损害发生率差异无统计学意义(P>0.05)。观察组年龄越小,心肌、肝、肾损害发生率越高,差异均有统计学意义(P<0.01)。结论婴幼儿RV肠炎常合并心、肝、肾损害,其发生率与失水程度无明显相关性,且年龄越小损害发生率越高。

Objective To discuss the relationship between rotavirus（RV） enteritis and myocardial,hepatic and renal damage in infants.Methods 126 cases infants with diarrhea were divided into observation group（RV antigen-positive group） and control group（RV antigen negative group） by the detected results of rotavirus antigens.Analyzed the funcions of heart,liver and kidney in two groups.Results The rates of myocardial,hepatic and renal damage in observation group were higher than that in control group（P0.01）.But the rates were not differences in different degree of water deprivation（P0.05）.As the age was more small,the rate of myocardial,hepatic and renal damage in observation group were more higher,the difference had statistical significance（P0.01）.Conclusion RV enteritis in infants is often associated with myocardial,hepatic,renal damage,the rates of myocardial,hepatic and renal injury were no relationship between with water deprivation,and the age is so small and the rate is so high.