妇产科围手术期抗菌药物应用调查分析

Survey and analysis of antibacterial agents' application for obstetrics and gynecology patients during perioperative period

目的了解本院妇产科围手术期预防性应用抗菌药物情况,评价用药合理性。方法随机抽取2010年妇产科手术患者287例,设计调查评定表,对抗菌药物在妇产科手术中的使用进行统计分析。结果 287例患者均应用了预防性抗菌药物,涉及抗菌药物7类23种,抗菌药物单用、二联和三联用药分别为83例(28.92%)、192例(66.90%)和12例(4.18%),抗菌药物联合使用204例(71.08%)中,最常见的联用形式为头孢菌素类+硝基咪唑类;术后用药时间太长不合理高达271例(94.42%),平均用药疗程为(6.04±0.62)d。结论本院妇产科围手术期抗菌药物使用仍存在不足,应加强抗菌药物的使用管理,规范围手术期抗菌药物的使用,临床药师应参与个体化给药方案,提高本院抗菌药物的合理使用。

Objective To investigate the prophylactic use of antimicrobial agents for obstetrics and gynecology patients during perioperative period in this hospital,and evaluate the rationality of drug use.Methods 287 obstetrics and gynecology patients in perioperative period were randomly chosen in this hospital in 2010,and the antibacterial agents′ application in obstetrics and gynecology operation was statistically analyzed by designed forms of investigation and evaluation.Results All of the 287 patients received antibiotics,which involved 7 categories and 23 varieties.The antibiotics alone,two and triple together were 83（28.92%）,192（66.90%） and 12（4.18%） retspectively.Of 204 cases（71.08%） which were joint usage,the most common form was cephalosporins and nitroimidazole.271（94.42%） cases was invoved in irrationaly use with a too long medication time after operation,and the average treatment duration was（6.04±0.62）d.Conclusion The antibacterial agents′ application for obstetrics and gynecology patients during perioperative period in this hospital still exists shortness.We should strengthen the management of antibacterial agents use,regulate the usage during perioperative period,and the clinical pharmacists should involve in individualized drug administration programs,so as to the improve the rational use of antibiotics in this hospital.