(±)-磷酸-氢-1,1′-联-2,2′-萘酯[(±)-BNP]的制备与拆分

PREPARATION AND RESOLUTION OF (±)-1,1- BINAPHTHYL 2,2′-DIYL HYDROGEN PHOSPHATE [(±) BNP]

以２－萘酚为原料经联苯、磷酰化、水解等反应制备了（±）－ＢＮＰ。后者用辛可宁拆分，经处理后得Ｓ－（＋ ）－ＢＮＰ和Ｒ－（－ ）－ＢＮＰ。

BNP was prepared by 3 step reactions from 2 Naphthol, and resolved into S (+) BNP and R (-) BNP via the cinchonine salt.