苯直接羟化制苯酚的新工艺

A new process for the direct hydroxylation of benzene to phenol

提出了TS-1分子筛为催化剂、十六烷基三甲基溴化铵为相转移催化剂、氨水为调节剂以及双氧水为氧化剂的苯直接羟化制苯酚的新工艺。考察了反应温度、反应时间、氧化剂用量和调节剂种类对苯直接羟化反应的影响。确定了反应的最佳条件,当反应时间为2 h,反应温度为313 K,氨水、催化剂、双氧水、相转移催化剂、苯五者物质的量之比为2.80∶0.10∶2.52∶0.005∶1时,苯酚产率可达66.32%。

A new process is reported for the direct hydroxylation of benzene to phenol using TS-1 zeolite as a catalyst,cetyltrimethylammonium bromide as a phase transfer catalyst,ammonia,ammonium carbonate or urea as a regulator,and hydrogen peroxide as an oxidant.The influences of key reaction parameters,including reaction temperatures and times,the catalyst amount,and the type of regulator on the reaction were also studied.Finally,the optimum reaction conditions were determined.The maximum yield of phenol can reached 66.32% when the reaction time was 2h,the reaction temperature was 313K,and the molar ratio of ammonia： catalyst： hydrogen peroxide： phase transfer catalyst： benzene was 2.80∶0.10∶2.52∶0.005∶1,respectively.