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Laboratory Detection and Diagnosis of Filoviruses 被引量:6

Laboratory Detection and Diagnosis of Filoviruses
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摘要 Ebola virus(EBOV) and Marburg virus(MARV),belonging to the Filoviridae family,emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates.As high as 50-90% mortality,filoviruses can cause significant threats to public health.However,so far no specific and efficient vaccine has been available,nor have other treatment methods proved to be effective.It is of great importance to detect these pathogens specific,rapidly and sensitively in order to control future filovirus outbreaks.Here,recent progresses in the development of detection and diagnosis methods for EBOV and MARV are summarized. Ebola virus (EBOV) and Marburg virus (MARV), belonging to the Filoviridae family, emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates. As high as 50-90% mortality, filoviruses can cause significant threats to public health. However, so far no specific and efficient vaccine has been available, nor have other treatment methods proved to be effective. It is of great importance to detect these pathogens specific, rapidly and sensitively in order to control future filovirus outbreaks. Here, recent progresses in the development of detection and diagnosis methods for EBOV and MARV are summarized
出处 《Virologica Sinica》 SCIE CAS CSCD 2011年第2期73-80,共8页 中国病毒学(英文版)
关键词 FILOVIRUS Ebola virus (EBOV) Marburg virus (MARV) Enzyme-linked immunosorbent assay(ELISA) Polymerase chain reaction (PCR) 埃博拉病毒 实验室检测 诊断方法 丝状 灵长类动物 公众健康 死亡率 病原体
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