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冠状动脉粥样硬化性心脏病高危患者的强化降脂与瑞舒伐他汀 被引量:8

Rosuvastatin and Intensive Lipid Lowering in High Risk Patients with Coronary Heart Disease
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摘要 瑞舒伐他汀具有独特的临床药理特点,其降脂疗效、安全性、成本-效益比均优于其他他汀类药物,具有降脂疗效以外的"多效性",是冠状动脉粥样硬化性心脏病高危患者强化降脂、减少心血管事件的最佳选择,呼吁瑞舒伐他汀能早日在基层医疗单位普及。 Rosuvastatin has unique clinical pharmacology characteristics including: lipid-lowering effects,and a safety and cost-benefit ratio that is superior to other statins.It also has many curative effects aside from lipid-lowering,called "pleiotropy" effects.This makes it the best choice for high risk coronary heart disease patients to intensively lower their lipids,and reduce cardiovascular events.This article reviews the benefits of using rosuvastatin for patients in a basic-level medical unit as early as possible.
作者 魏子秀 张梅
出处 《心血管病学进展》 CAS 2011年第2期224-227,共4页 Advances in Cardiovascular Diseases
关键词 冠状动脉粥样硬化性心脏病 瑞舒伐他汀 低密度脂蛋白胆固醇 多效性 coronary atherosclerotic heart disease rosuvastatin low-density lipoprotein cholesterol pleiotropy
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  • 1Steven E. Nissen,Stephen J. Nicholls,Ilks Sipahi,Peter Libby,Joel S. Raichlen,Christie M. Ballantyne,Jean Davignon,Raimund Erbel,Jean Charles Fruchart,Jean-Claude Tardif,Paul Schoenhagen,Tim Crowe,Valerie Cain,Kathy Wolski,Marlene Coormastic,E. Murat Tuzcu,仝其广(译),王淑敏(译),胡大一(校).极高强度他汀治疗对冠状动脉粥样硬化消退的影响——ASTEROID试验[J].美国医学会杂志(中文版),2006,25(4):215-223. 被引量:346
  • 2Cannon CP, Braunwald E, McCabe CH, et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med. 2004;350:1495-1504.
  • 3LaRosa JC, Grundy SM, Waters DD, et al; Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005;352:1425-1435.
  • 4Pedersen TR, Faergeman O, Kastelein J J, et al; Incremental Decrease in End Points Through Aggressive Lipid Lowedng (IDEAL) Study Group. High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study:a randomized controlled trial. JAMA. 2005;294:2437-2445.
  • 5Grundy SM, Cleeman JI, Merz CN, et al; Coordinating Committee of the National Cholesterol Education Program. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel Ⅲ Guidelines. J Am Coll Cardiol. 2004;44:720-732.
  • 6Blankenhom DH, Azen SP, Kramsch DM, et al;MARS Research Group. Coronary angiographic changes with Iovastatin therapy: the Monitored Atherosclerosis Regression Study (MARS). Ann Intern Med.1993;119:969-976.
  • 7Waters D, Higginson L, Gladstone P, et al. Effects of monotherapy with HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed be serial quantitaUve arteriography: the Canadian Coronary Atherosclerosis Intervention Trial(CCAIT). Circulation. 1994;89:959-968.
  • 8Jukema JW, Bruschke AV, van Boven A J, et al. Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels: the Regression Growth Evaluation Statin Study (REGRESS). Circulation. 1995;91:2528-2540.
  • 9Pitt B, Mancini GB, Ellis SG, Rosrnan HS, Park J-S,McGovem ME. Pravastatin limitaUon of atherosclerosis in the coronary arteries (PLAC Ⅰ): reduction in atherosclerosis progression and clinical events. J Am Coll Cardiol. 1995;26:1133-1139.
  • 10Brown G, Albers J J, Fisher LD, et al. Regression of coronary artery disease as a result of intensive lipidlowering therapy in men with high levels of apolipoprotein B. N Engl J Med. 1990;323:1289-1298.

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  • 1常琦,金萍,张晓玲,丁琼,王春华.动脉粥样硬化早期干预与预防冠心病中的作用[J].中国老年学杂志,2014,34(9):2367-2369. 被引量:14
  • 2邹淑婷,张惠兰.通心络治疗冠心病126例临床研究[J].时珍国医国药,2006,17(6):1044-1044. 被引量:2
  • 3Rosuvastatin Registration Clinical Trial Group.Cardiovascular Institute and Fu Wai Hospital,Peking Union Medical College and Chinese Academy of Medical Science,Beijing 100037,China.瑞舒伐他汀治疗中国高胆固醇血症患者疗效和安全性的随机双盲多中心对照研究[J].中华心血管病杂志,2007,35(3):207-211. 被引量:117
  • 4王晖,蒋丹.丹参注射液治疗冠心病心绞痛疗效及对血小板聚集率的影响[J].吉林中医药,2007,27(10):14-15. 被引量:19
  • 5Sergienko IV,Samoǐlenko EIu,Masenko VP,et al.Effect of therapy with rosuvastatin on lipid spectrum,factors of inflammation and endothelial function in patients with ischemic heart disease[J].Kardiologiia,2006,46(5):4-8.
  • 6Canou-Poitrine F,Luc G,Mallat Z,et al.Systemic chemokine levels,coronary heart disease,and ischemic stroke events:the PRIME study[J].Neurology,2011,77(12):1165-1173.
  • 7Ridker PM,Danielson E,Fonseca FA,et al.Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein[J].N Engl J Med,2008,359(21):2195-2207.
  • 8Perk J,De Backer G,Gohlke H,et al.European guidelines on cardiovascular disease prevention in clinical practice(version2012)[J].Eur Heart J,2012,33(13):1635-1701.
  • 9Philip Barter.Lessons Learned from the Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events (ILLUMINATE) Trial[J].The American Journal of Cardiology.2009(10)
  • 10Daniel Bloomfield,Gary L. Carlson,Aditi Sapre,Diane Tribble,James M. McKenney,Thomas W. Littlejohn,Christine McCrary Sisk,Yale Mitchel,Richard C. Pasternak.Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients[J].American Heart Journal.2009(2)

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