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效应性T细胞亚群Th17与动脉粥样硬化 被引量：4

New Subset of Effector T Cells Th17 and Atherosclerosis
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摘要 效应性T细胞亚群Th17是新近发现的效应性T细胞的又一亚群,因分泌细胞因子IL-17而得名。Th17通过分泌多种效应分子如白细胞介素17、17F、21和肿瘤坏死因子-α等与慢性炎症性疾病、自身免疫性疾病和肿瘤等疾病密切相关。研究发现,动脉粥样硬化的发生发展也与Th17功能的异常密切相关,现拟就此进行综述。 Th17 characterized by the production of interleukin（IL）-17 is a newly founded subset of CD4 T effect cells.Th17 cytokines include IL-17,IL-17F,IL-21,tumor nuclear factor-α and so on.Th17 have been linked to many chronic inflammatory diseases,autoimmune diseases and tumor.Several data indicated that Th17 response may play an important role in the development and progression of atherosclerosis.In this review,we will introduce the role of Thl 7 in atherosclerosis.
作者 吉庆伟 曾秋棠 林英忠
机构地区 广西自治区人民医院心内科 华中科技大学同济医学院附属协和医院
出处 《心血管病学进展》 CAS 2011年第2期238-241,共4页 Advances in Cardiovascular Diseases
基金 国家自然科学基金项目资助(No:81070237)
关键词 效应性T细胞 TH17 动脉粥样硬化 effector T cells Th17 atherosclerosis
分类号 R543.5 [医药卫生—心血管疾病]
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参考文献20

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共引文献17

同被引文献75

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心血管病学进展
2011年 第2期

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