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G蛋白信号转导异常与阿尔茨海默病 被引量:3

Abnormalities of G protein signal transduction in AD
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摘要 AD是一种以进行性认知功能减退为特征的神经退行性疾病。流行病学调查表明:在65岁以上人群中AD的发病率为5%~10%,85岁以上的老年人中发病率约为25%^[1]。随着人口老龄化趋势的进展,AD已成为威胁人类生命的主要疾病.其致死率仅次于心脏病、肿瘤和中风。AD根据家族史可分为家族性AD(FAD)和散发性AD(SAD)。
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2011年第3期319-321,共3页 Chinese Journal of Neuromedicine
基金 国家自然科学基金(30772839,30873302) 天津市应用基础及前沿技术研究计划重点项目(08JCZDJCl5800)
关键词 阿尔茨海默病 淀粉样蛋白 TAU蛋白质类 Alzheimer's disease Amyloid beta Tau protein
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参考文献21

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