老年骨折患者焦虑抑郁与C反应蛋白的关系

Relationship between anxiety and depression in elderly patients with fractures and C reactive protein

目的:研究老年骨折患者情绪焦虑抑郁状态与高敏C反应蛋白(hs-CRP)的关系。方法:2008年3月至2010年4月首次入住我院老年病科及骨科的72例老年骨折患者,于入院当日进行汉密顿焦虑量表(HAMA)、汉密顿抑郁量表(HAMD)评定,记录年龄、性别等相关临床数据。次日晨抽取空腹状态下外周静脉血,监测血浆hs-CRP。结果:焦虑组、抑郁组、焦虑抑郁共病组患者血浆hs-CRP与非焦虑非抑郁组血浆hs-CRP之间差异有统计学意义(P<0.05);焦虑组、抑郁组hs-CRP水平与各量表评分呈正相关。结论:老年骨折患者焦虑抑郁状态与体内炎性反应有关。

Objective：To research the relationship between anxiety and depression in elderly patients with fractures and high sensitivity C reactive protein.Methods：Totally 72 elderly patients with fractures who for the first time admitted to the Department of Geriatrics and orthopaedics were selected from March 2008 to April 2010.To assess respectively Hamilton anxiety scale.Hamilton depression scale and record age.gender and other relevant clinical data on admission day.To collect peripheral blood with fasting state in the next morning and monitor the hs-CRP in the plasma.Results：Anxiety group.depression group.anxiety and depression in elderly patients and non-anxiety and non-depressed group had significant difference in plasma hs-CRP（P0.05）;The hs-CRP level in anxiety group.depression group and the scale score was positively correlated.Conclusion：Anxiety and depression in elderly patients with closed fractures relate to the inflammatory response in the body.