血清同型半胱氨酸水平与乳腺肿瘤的关系分析

Analysis of relationship between serum homocysteine level and breast tumor

目的探讨乳腺癌及其术后和乳腺良性肿瘤患者与血清同型半胱氨酸(Hcy)关系。方法采用循环酶法检测90例乳腺癌、乳腺癌术后及乳腺良性肿瘤患者血清Hcy水平,并与50例健康体检者(健康对照组)检测结果比较。结果乳腺癌组与乳腺良性肿瘤组、健康对照组之间血清Hcy水平的差异无统计学意义(P>0.05)。乳腺癌术后组与健康对照组之间血清Hcy水平差异有统计学意义(P<0.05)。结论血清Hcy与乳腺肿瘤的发生、发展无相关性。

Objective To investigate the relationship between serum homocysteine（Hcy）and the patients with breast cancer,after surgery or with benign breast tumor.Methods To test the serum Hcy levels in 90 patients with breast cancer,after surgery,or with benign breast tumor by enzymatic cycling assay.To compare the test results with those of 50 healthy people.Results As for serum Hcy level,there was no significant difference between the patients with breast cancer or benign breast tumor and healthy people（P〉0.05）,but significant difference（P〈0.05）between the patients after surgery and healthy people.Conclusion Serum Hcy level is independent of the growth and development of breast tumor.