β2肾上腺素受体基因多态性的研究进展
摘要
β2肾上腺素受体(β2AR)是鸟嘌呤核苷蛋白耦联类受体中的一种,是由单一肽链形成7个仅螺旋往返穿透细胞膜而最终形成的具有亲水性的蛋白质。β2AR在机体多种组织细胞中均有表达,包括支气管和血管平滑肌细胞、心肌细胞、
出处
《临床内科杂志》
CAS
2011年第1期70-71,共2页
Journal of Clinical Internal Medicine
参考文献18
-
1Leineweber K, Brodde OE. Beta2-adrenoceptor polymorphisms: relation between in Vitro and in Vivo phenotypes. Life Sci, 2004, 74: 2803-2814.
-
2Taylor DR. Pharmacogenetics of beta2-agonist drugs in asthma. Clin Rev Allergy Immuno1,2006 ,31:247-258.
-
3Lima JJ, Mohamed MH, Self TH, et al. Importance of beta(2 ) adrencrgic receptor genotype, gender and race on albuterol-evoked bronchodilationin asthmatics. Pulm Pharmacol Ther, 2000,13 : 127-134.
-
4Van Veen A,wierenga EA, Westland R, et al. Limited beta2-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics. Resrfir Res .2006.7 : 19.
-
5姜远英.主编.药物基因组学.北京:人民卫生出版社,2006.291.
-
6Santillon AA, Camargo CA Jr, Ramirez-Rivera A, et al. Association be- tween beta2-adrenoceptor polymorphisms and asthma diagnosis among Mexican aduhs. J Allergy Clin Immuno1,2003,112 : 1095-1100.
-
7Taylor DR, Epton M J, Kennedy MA, et al. Bronchodilator responses in relation to beta2-adrenoceptor haplotype in patients with asthma. Am J Respir Crit Care Med ,2005,172:700-703.
-
8Zhang G,Hadyden CM, Khoo SK, et al. Assocition of haplotype of beta2adrenoceptor polymorphisms with lung function and airway responses in a pediatric cohort. Pediatr Pulmonol,2006 ,41:1233-1241.
-
9Hall IP, Blakey JD, A1 Balushi KA, et al. Beta2-adrenoceptor polymorphisms and asthma from Childhood to millddle age in the British 1958 birth cohort : a genetic assotion study. Lancet,2006,368:771-779.
-
10Ho HL,Harn HJ,Chen CJ,et al. Polymorphism of theβ2- ad2renoceptor in COPD in Chinese subjects. Chest,2001,120:1493 - 1499.
二级参考文献6
-
1Bel EH,Zwinderman AH,Timmers MC,et al.The protective effect of aβ2-agonist against excessive airway narrowing in re-sponse to bronchoconstriction stimuli in asthma and chronic ob-structive lung disease[].Thorax.1991
-
2Hopp RJ,Beutra AK,Watt GD.Genetic analysis of allergic dis-ease in twins[].The Journal of Allergy and Clinical Immunology.1990
-
3Ho LI,Harn HJ,Chen CJ,et al.Polymorphismof theβ2-ad-renoceptor in COPD in Chinese subjects[].Chest.2001
-
4Reishaus E,Lnnis M,Macntyre N,et al.Mutations in the gene encoding for theβ2-adrenergic receptor in normal and asth-matic subjects[].American Journal of Respiratory and Critical Care Medicine.1993
-
5Burows BR,Knudson J,Cline MG,et al.Quantitative relation-ship between cigarette smoking and ventilation function[].The American Review of Respiratory Disease.1977
-
6Hall I P,Weatley A,Wilding P,et al.Association of Glu27β2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects[].The Lancet.1995
共引文献7
-
1王成,田陆云.β_2-肾上腺素能受体多态性与慢性阻塞性肺疾病合并高血压的相关性[J].疑难病杂志,2009,8(8):510-512. 被引量:1
-
2朱鑫瀛,宋卫东.慢性阻塞性肺疾病患者外周血IL-2、IL-8、IL-10和T淋巴细胞亚群的变化及其意义[J].中国临床研究,2012,25(1):82-83. 被引量:6
-
3王成,杨皑岚,李华,毕鸿雁,傅玮萍,戴路明,陈芬,谭芳,符琴,田陆云.云南汉族老年人群β_2-AR基因Gln27Glu多态性与COPD合并原发性高血压相关性的初步研究[J].实用医学杂志,2012,28(7):1100-1103. 被引量:2
-
4张振芳,王在义.COPD基因研究进展[J].临床肺科杂志,2014,19(1):124-127. 被引量:6
-
5熊明媚,王健,钟南山,卢文菊.慢性阻塞性肺疾病相关基因组学研究[J].中华结核和呼吸杂志,2016,39(1):58-61. 被引量:10
-
6廖佩花,者炜,刘来新,张荣,张云君,甫尔哈提.吾守尔.新疆监测点40岁及以上人群慢性阻塞性肺疾病患病情况及影响因素分析[J].中国慢性病预防与控制,2018,26(8):576-579. 被引量:11
-
7刘嘉,严宝飞,曾明月,曾庆琪,杨海军,张景正.黄芩-金银花药对治疗新型冠状病毒肺炎潜在作用机制的网络药理学研究[J].世界中医药,2020,15(4):502-511. 被引量:31
-
1韩刚,王传坚.支气管哮喘的疗效分析[J].医学信息(下旬刊),2011,24(2):133-133.
-
2刘晓华,李大文,崔丽英.β_2肾上腺素受体基因多态性与支气管哮喘的关系[J].内蒙古医学杂志,2005,37(10):918-921.
-
3栗程,袁铭,郭文怡.西北汉族人群β_2肾上腺素受体基因多态性与原发性高血压的相关性研究[J].陕西医学杂志,2014,43(4):405-407. 被引量:1
-
4郭庆春,于建生,张为.卡介苗多糖核酸对支气管哮喘的预防效果观察——附193例报告[J].新医学,2008,39(11):716-718. 被引量:3
-
5廖伟.β_2肾上腺素受体遗传多态性与哮喘[J].国外医学(遗传学分册),2000,23(1):8-11. 被引量:2
-
6高金明,林耀广,邱长春,高君,马毅,刘怡雯,刘英.β_2肾上腺素受体基因多态性和支气管哮喘的关系[J].中国医学科学院学报,2002,24(6):626-631. 被引量:6
-
7潘永平,周世良.β_2肾上腺素受体基因多态性与支气管哮喘的关系[J].江西医学院学报,2003,43(1):136-138.
-
8戴路明,王曾礼,张亚平,刘凌,方利州,张剑青.β_2肾上腺素受体多肽16位基因型与夜间哮喘表现型的关系[J].四川大学学报(医学版),2004,35(1):32-34. 被引量:4
-
9潘永平,周世良,况九龙,饶纬华.β_2肾上腺素受体基因多态性与支气管哮喘的相关性研究[J].江西医学院学报,2005,45(4):44-47. 被引量:2
-
10陈丽丽.支气管哮喘的发病机制及临床药物治疗的进展[J].临床医药文献电子杂志,2015,2(35):7349-7350. 被引量:5