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ANA和ANA谱3联合检测在3种自身免疫性疾病中的临床应用价值 被引量:2

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摘要 目的探讨ANA、ANA谱3联合检测在自身免疫性疾病(AD)诊断中的应用。方法 ANA检测采用间接免疫荧光法;ANA谱3检测采用免疫印迹法。结果 200例AD患者中,系统性红斑狼疮(SLE)组的ANA、Sm、dsDNA、核小体、组蛋白、核糖体P蛋白与其他各组对比,差异有统计学意义(P<0.05);干燥综合征(SS)组中的SS-A、Ro-52、SS-B与其他各组对比,差异有统计学意义(P<0.05)。结论 ANA、ANA谱3的联合检测在AD,特别是SLE和SS的诊断中具有互补性,有利于提高检出率。
作者 龚丽坤
出处 《国际检验医学杂志》 CAS 2011年第3期412-413,共2页 International Journal of Laboratory Medicine
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  • 1Goldbach-Mansky R, Lipsky PE. New concepts in the treatment of rheumatoid arthritis[J]. Annu Rev Med, 2003, 54: 197-216.
  • 2Schellekens GA, Visser H, de-Jong BA, et al. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide [J]. Arthritis Rheum, 2000, 43 (1) : 155- 163.
  • 3Berglin E, Padyukov L, Sundin U, et al. A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis [J]. Arthritis Res Ther, 2004, 6(4) : R303- R308.
  • 4Girelli F, Foschi FG, Bedeschi E, et al. Is Anti Cyclic citrullinated peptide a useful laboratory test for the diagnosis of rheumatoid arthritis [J]? Allerg Immunol (Paris), 2004, 36(4), 127-130.
  • 5Mediwake R, Isenberg DA, Schellekens GA, et al. Use of anticitrullinated peptide and anti RA33 antibodies in distinguishing erosive arthritis in patients with systemic lupus erythematosus and rheumatoid arthritis[J]. Ann Rheum Dis, 2001, 60(1):67-68.
  • 6Salvador G, Gomez A, Vinas O, et al. Prevalence and clinical significance of anti-cyclic citrullinated peptide and antikeratin antibodies in palindromic rheumatism. An abortive form of rheumatoid arthritis[J]? Rheumatology (Oxford), 2003, 42(8):972- 975.
  • 7Saraux A, Berthelot JM, Devauehelle V, et al. Value of antibodies to eitrulline-eontaining peptides for diagnosing early rheumatoid arthritis. J Rheumatol, 2003, 30(12) : 2535-2539.
  • 8Yazici Y, Paget SA. Elderly onset rheumatoid arthritis[J]. Rheum Dis Clin North Am, 2000, 26(3):517-526.
  • 9Sakata M, Tsuruha JI, Masuko-Hongo K, et al. Autoantibodies to osteopontin in patients with osteoarthritis and rheumatoid arthritis[J]. J Rheumatol, 2001, 28(7) : 1492-1495.
  • 10El-Gabalawy HS, Wilkins JA. Anti-Sa antibodies: prognostic and pathogenetic significance to rheumatoid arthritis [J]. Arthritis Res Ther, 2004, 6(2): 86-89.

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