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运动训练对中枢抑制蛋白和脑可塑性的影响

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摘要 运动训练对中枢神经系统有促进再生和解除抑制两方面的作用。中枢神经抑制蛋白参与了中枢神经构建精确神经网络的过程,是功能重塑不可替代的因素之一。单纯抑制中枢神经抑制蛋白可能对功能重塑作用不大。运动训练可能限制中枢神经轴突抑制蛋白的表达,促进轴突再生从而促进脑功能重塑过程。
出处 《按摩与康复医学》 2011年第1期34-37,共4页 Chinese Manipulation and Rehabilitation Medicine
基金 基金项目:广东省科技计划项目资助课题(项目编号20078031501008)
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参考文献35

  • 1Johansson BB,Grabonski M.Functional recover after brain infarcion:Plasticity and neural transplantation.Brain Pathol 1994,4(1 ) : L85 -95.
  • 2Richardson PM,McGuinness UM Aguavo AJo Axons from CNS neurons regenerate into PNS grafts. [J]. Nature, 1980,284 : 264-265.
  • 3Johansson BB. Regeneration and plasticity in the brain andspinal cord [J]. J Cereb Blood Flow Metab,2007,27 (8): 1417-1430.
  • 4Xiang S,Pan W,Kastin AJ. Strategies to create a regenerating environment for the injured spinal cord [J]. Curt" Pharm Des, 2005,11(10) : 1267-1277.
  • 5Jones LL,Sajed,D,Tuszynski,MH. Axonal regeneration throughregions of chondroitin sulfate proteoglycan deposition afterspinal cord injury:a balance of permissiveness and inhibition[J]. J of Neuroscience, 2003,23(28): 9276-9288.
  • 6Jain N,Florence SL,Kaas JH.Reorganization of soma-tosensory cortex after nerve and spinal cord injury.[J]News Physiol Sci, 1998 ; 13(6): 143-149.
  • 7Thomas SL,Gorassini MA. Increases in corticospinal tract function by treadmill training after incomplete spinal cordinjury[J].J Neurophysiol, 2005,94(4) : 2844-2855.
  • 8Hutchinson KJ,G6 mez - Pinilla F,Crowe MJ,etal. Three exercise paradigms differentially improve sensory recovery after spinal cord contusion in rats [J]. Brain,2004,127: 1403-1414.
  • 9Tong L,Shen H,Perreau VM,etal. Effects of exercise on gene- expression profile in the rat hippocampus [J]. NeurobiolDis, 2001,8(6) : 1046-1056.
  • 10Vaynman S,Ying Z,Gomez - Pinilla F. Exercise induces BDNF and synapsin I to specific hippocampal subfields. [J]. J Neurosci Res, 2004,76(3). 356-362.

二级参考文献33

  • 1[1]Dombovy ML.Understanding stroke recovery and rehabilitation:Current and emerging approaches[J].Curt Neurol Neurosci Rep,2004,4:31-35.
  • 2[2]Dettmers C,Teske U,Hamzei F,et al.Distributed form of constraint-induced movement therapy improves functional outcome and quality oflife after stroke[J].Arch Phys Med Rehabil,2005.86:204-209.
  • 3[3]Mark VW,Taub E.Constraint-induced movement therapy for chronic stroke hemiparesis and other disabilities[J].Restor Neurol Neurosci,2004,22:317-336.
  • 4[4]Zhao CS,Puurunen K,Schallert T,et al.Effect of cholinergic medication,before and after focal photothrombotic ischemic cortical injury,on histological and functional outcome in aged and young adult rats[J].Behav Brain Res,2005,156:85-94.
  • 5[5]Butefisch CM.Plasticity in the human cerebral cortex:Lessons from the normal brain and from stroke[J].Neuroscientist,2004,10:163-173.
  • 6[6]Taub E,Uswatte G,Morris DM.Improved motor recovery after stroke and massive cortical reorganization following constraint-induced movement therapy[J].Phys Med Rehabil Clin N Am,2003,14:S77-S91,ix.
  • 7[7]Schwab ME.Nogo and axon regeneration[J].Curr Opin Neurobiol,2004,14:118-124.
  • 8[8]He Z,Koprivica V.The nogo signaling pathway for regeneration block[J].Annu Rev Neurosci,2004,27:341-368.
  • 9[9]Wang F,Liang Z,Hou Q,et al.Nogo-a is involved in secondary axonal degeneration of thalamus in hypertensive ratg with focal cortical infarction[J].Neurosci Lett,2007,417:255-260.
  • 10[10]Tsai SY,Markus TM,Andrews EM,et al.Intrathecal treatment with anti-nogo-a antibody improves functional recovery in adult rats after stroke[J].Exp Brain Res,2007,182:261-266.

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