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抗肿瘤免疫的新策略:揭开环磷酰胺未知的面纱 被引量：2

New Strategy of Cancer Immunotherapy:Unveilling the Unknown Face of Cyclophosphamide
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摘要 环磷酰胺是临床常用的抗肿瘤化疗药物以及用于器官移植和自身免疫性疾病的免疫抑制剂。但最近的研究发现低剂量的环磷酰胺能够选择性地杀伤CD4+CD25+调节性T细胞,从而增强抗肿瘤免疫应答。文章简略介绍这一新的肿瘤免疫治疗研究。
作者 黄波 沈关心
机构地区 华中科技大学同济医学院生物化学与分子生物学系 华中科技大学同济医学院免疫学系
出处 《中国肿瘤》 CAS 2011年第2期98-99,共2页 China Cancer
关键词 肿瘤 免疫治疗 环磷酰胺 调节性T细胞
分类号 R730.51 [医药卫生—肿瘤]
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参考文献10

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同被引文献21

  • 1李永红,于梅艳,王瑞,刘宏民.薄层色谱法测定β-氨基醇类药物中间体的含量[J].郑州大学学报（理学版）,2008,40(1):94-96. 被引量：3
  • 2陶建伟,孟建良,严静山,陆庆宁.气相色谱法测定反应液中的3-氨基丙醇[J].上海应用技术学院学报（自然科学版）,2004,4(4):294-296. 被引量：4
  • 3徐应淑,宋宝安.手性氨基醇的研究进展[J].遵义医学院学报,2006,29(3):295-298. 被引量：4
  • 4Erika V,Laura S,Alexander E. Chemotherapy with immunogenic cell death inducers[J].Oncolmmunology,2013,(3):5101-5111.
  • 5Dmitri VK,Abhishek DG,Agnieszka K. Immunogenic cell death and DAMPs in cancer therapy[J].{H}Nature Reviews Cancer,2013,(1):860-875.
  • 6Jitka F,Petra K,Anna F. Human tumor cells killed by anthracyclines induce a tumor-specific immune response[J].{H}CANCER RESEARCH,2011,(1):4821-4833.
  • 7Michel O,Antoine T,Francois G. Calreticulin exposure dictates the immunogenicity of cancer cell death[J].{H}Nature Medicine,2007,(10):54-61.
  • 8Sukkurwala AQ,Martins I,Wang Y. Immunogenic calreticulin exposure occurs through a phylogenetically conserved stress pathway involving the chemokine CXCL8[J].Cell Death & Differentiation,2013,(2):54-61.
  • 9Chihiro Y,Masanaka S,Tomokazu O. Critical roles of a dendritic cell subset expressing a chemokine receptor,XCRl[J].{H}Journal of Immunology,2013,(12):6071-6082.
  • 10冯雅斌,杜靓,温静.薄层色谱法在药物分析中的应用及研究进展[J].疾病监测与控制,2011,5(1):60-63. 被引量：52

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中国肿瘤
2011年 第2期

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